{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T05:10:40Z","timestamp":1778821840287,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T00:00:00Z","timestamp":1772755200000},"content-version":"vor","delay-in-days":5,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100013924","name":"Wirtschaftsagentur Wien","doi-asserted-by":"publisher","award":["4182248"],"award-info":[{"award-number":["4182248"]}],"id":[{"id":"10.13039\/501100013924","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anim Models and Exp Med"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Biomedical research and preclinical testing in large animal models are essential for developing and evaluating new medical devices. This ovine study presents a stepwise implantation protocol and initial experiences with a wireless blood pressure implant sensor, enabling continuous telemetric monitoring in sheep. Adult female Jezersko\u2010Sol\u010dava sheep underwent implantation of a wireless blood pressure sensor into the ascending aorta via the right carotid artery. The body of the device can was positioned subcutaneously in the lower neck region. After skin closure, a computed tomography scan was performed to verify sensor tip location. If malposition was detected, surgical revision was undertaken immediately. Wireless blood pressure monitoring was conducted over a 24\u2009h period in a custom\u2010designed sheep barn. Twelve adult female sheep successfully underwent the implantation procedure, with no major complications reported. Sensor catheter revision was required in three animals (25%). The mean duration of the procedure (from incision to skin closure) was 36\u2009\u00b1\u200910\u2009min. During the 24\u2009h monitoring period, the average systolic and diastolic blood pressures were 93\u2009\u00b1\u20096 and 65\u2009\u00b1\u20095\u2009mmHg, respectively. Large animal models, particularly sheep, are indispensable in cardiovascular device research due to their anatomical and physiological similarities to humans. This study demonstrates a rapid, minimally invasive protocol for wireless blood pressure sensor implantation in sheep, offering a valuable platform for chronic telemetric monitoring in the development of cardiovascular medical devices.<\/jats:p>","DOI":"10.1002\/ame2.70159","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T10:22:03Z","timestamp":1772965323000},"page":"630-638","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Wireless blood pressure sensor implantation in sheep: A\u00a0detailed technique"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4493-4326","authenticated-orcid":false,"given":"David","family":"Santer","sequence":"first","affiliation":[{"name":"Center for Biomedical Research and Translational Surgery Medical University of Vienna  Vienna Austria"},{"name":"Medical Faculty of the University of Basel  Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Ecker","sequence":"additional","affiliation":[{"name":"Ascense Medical GmbH  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Radloff","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research and Translational Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Heissl","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research and Translational Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smruti","family":"Mirchandani","sequence":"additional","affiliation":[{"name":"Ascense Medical GmbH  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabine","family":"Leitner","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research and Translational Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-4403-4349","authenticated-orcid":false,"given":"Bruno","family":"Mora","sequence":"additional","affiliation":[{"name":"Department of Thoracic and Cardiovascular Anesthesia and Intensive Care, General Hospital Vienna Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Czerny","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart Center Freiburg\u2010Bad Krozingen  Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roman","family":"Gottardi","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery University Heart Center Freiburg\u2010Bad Krozingen  Freiburg Germany"},{"name":"Faculty of Medicine Albert Ludwigs University Freiburg  Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Moore","sequence":"additional","affiliation":[{"name":"Ascense Medical GmbH  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruno K.","family":"Podesser","sequence":"additional","affiliation":[{"name":"Center for Biomedical Research and Translational Surgery Medical University of Vienna  Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2026,3,6]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000158419.98675.d7"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.21.5.714"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.17236\/sat00325"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2020.07.004"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/ani9100754"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9149(78)90128-5"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eur137"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2014.10.004"},{"issue":"4","key":"e_1_2_10_10_1","first-page":"368","article-title":"Non\u2010invasive blood pressure measurement in animals: part 1\u2014techniques for 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Accessed November 18 2025.https:\/\/www.datasci.com\/products\/implantable\u2010telemetry\/large\u2010animal"},{"key":"e_1_2_10_15_1","unstructured":"Techniques & measurements. Accessed November 18 2025.https:\/\/www.emkatech.com\/product\/easytel\u2010large\u2010animals\/techniques\u2010and\u2010measurements"},{"key":"e_1_2_10_16_1","article-title":"Wireless telemetry device implantation in a Fontan ovine model for continuous and long\u2010term hemodynamic monitoring","volume":"219","author":"Guo M","year":"2025","journal-title":"J Vis Exp"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1258\/la.2010.010059"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0442.1993.tb00677.x"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.02.018"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vascn.2018.03.006"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1177\/026119299502300306"}],"container-title":["Animal Models and Experimental Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ame2.70159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ame2.70159","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ame2.70159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T04:32:31Z","timestamp":1778819551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ame2.70159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,3]]}},"alternative-id":["10.1002\/ame2.70159"],"URL":"https:\/\/doi.org\/10.1002\/ame2.70159","archive":["Portico"],"relation":{},"ISSN":["2576-2095","2576-2095"],"issn-type":[{"value":"2576-2095","type":"print"},{"value":"2576-2095","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3]]},"assertion":[{"value":"2025-09-29","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}