{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T11:05:42Z","timestamp":1706180742811},"reference-count":21,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,6,30]],"date-time":"2015-06-30T00:00:00Z","timestamp":1435622400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:sec><jats:title>Aims<\/jats:title><jats:p>To retrospectively evaluate the correlation between multidetector\u2010row computed tomography findings of acute appendicitis and the pathological status of acute appendicitis, and evaluate the capability of multidetector\u2010row computed tomography to predict the pathological status of acute appendicitis in children.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The presence of a distended appendix (&gt;6\u2009mm in transverse diameter) was used as a primary sign to indicate the presence of appendiceal inflammation. The presence of appendiceal wall thickening (&gt;1\u2009mm) and enhanced appendiceal wall continuity were also used as predictive findings to reflect the degree of progression of acute appendicitis on multidetector\u2010row computed tomography findings. The findings of each individual case were classified into four grades. The final pathological diagnosis was classified into four groups: normal findings, only mucosal inflammation, inflammation with intramural spreading, and gangrenous. The relationship between the pathological grades and computed tomography grades was analyzed using <jats:styled-content style=\"fixed-case\">S<\/jats:styled-content>pearman's rank correlation test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Four of six cases in Grade 0 reflected normal appendiceal findings (66.7%) and 3 of 5 cases in Grade <jats:styled-content style=\"fixed-case\">I<\/jats:styled-content> reflected only mucosal inflammation status (60.0%). Forty\u2010four of 51 cases in Grade <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> reflected intramural inflammation status (86.3%), and 40 of 57 cases in Grade <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> reflected gangrenous status (70.2%). The multidetector\u2010row computed tomography grade was significantly correlated to the pathological grade with Spearman's rank correlation coefficient of 0.689 (<jats:italic>P<\/jats:italic>\u2009&lt;\u20090.001).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There was a close relationship between the multidetector\u2010row computed tomography imaging findings and the pathological findings. This preoperative information is extremely useful for decision\u2010making in the treatment strategy for acute appendicitis in children.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.131","type":"journal-article","created":{"date-parts":[[2015,6,30]],"date-time":"2015-06-30T06:35:37Z","timestamp":1435646137000},"page":"21-25","source":"Crossref","is-referenced-by-count":3,"title":["Contrast\u2010enhanced multidetector\u2010row computed tomography can predict pathological findings of acute appendicitis in children"],"prefix":"10.1002","volume":"3","author":[{"given":"Naoki","family":"Hashizume","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery Niigata City General Hospital  Niigata City Fukuoka Japan"},{"name":"Department of Pediatric Surgery Kurume University School of Medicine  Kurume Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasushi","family":"Iinuma","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yutaka","family":"Hirayama","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohju","family":"Nitta","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisataka","family":"Iida","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoi","family":"Shiotani","sequence":"additional","affiliation":[{"name":"Department of Radiology Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Shibuya","sequence":"additional","affiliation":[{"name":"Department of Pathology Niigata City General Hospital  Niigata City Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minoru","family":"Yagi","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery Kurume University School of Medicine  Kurume Fukuoka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,6,30]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2004.05.011"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002470050023"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.176.1.1760031"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2006.10.005"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1053\/jpsu.2003.50110"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.08.038"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-008-9415-5"},{"key":"e_1_2_7_9_1","first-page":"242","article-title":"Enhanced multidetector\u2010row computed tomography (MDCT) in the diagnosis of acute appendicitis and its severity","volume":"23","author":"Miki T","year":"2005","journal-title":"Radiat. 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