{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T13:01:14Z","timestamp":1782910874160,"version":"3.54.5"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T00:00:00Z","timestamp":1519171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>This study aimed to clarify the characteristics of patients who presented with severe hypermagnesemia and subsequently underwent emergency hemodialysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We investigated the age, gender, complications, clinical symptoms, causal drugs, electrocardiogram findings, and laboratory data of 15 patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Magnesium oxide had been administered in all cases and 14 patients were over 65\u00a0years old. The male\u00a0:\u00a0female ratio was 6:9. Chief complaints included a disturbance of consciousness, hypotension, bradycardia, and respiratory failure. The median serum magnesium value before hemodialysis was 6.0 (3.7\u201318.6)\u00a0mg\/<jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>. The daily dosage of magnesium oxide was \u2264\u00a02.0\u00a0g in 12 cases. The median serum creatinine value before hemodialysis was 5.39 (0.54\u201310.29)\u00a0mg\/<jats:styled-content style=\"fixed-case\">dL<\/jats:styled-content>. However, in two cases, the creatinine value was not elevated. Complications of acute kidney injury exacerbated the hypermagnesemia in nine cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We recommend that the serum magnesium value should be measured in older patients who are taking magnesium oxide and are showing signs and symptoms of a disturbance of consciousness, hypotension, bradycardia, and respiratory failure of an uncertain etiology, even if the serum creatinine value is not elevated or the dosage of magnesium oxide is within recommended levels.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.334","type":"journal-article","created":{"date-parts":[[2018,2,21]],"date-time":"2018-02-21T20:19:12Z","timestamp":1519244352000},"page":"222-229","source":"Crossref","is-referenced-by-count":43,"title":["The characteristics of patients with hypermagnesemia who underwent emergency hemodialysis"],"prefix":"10.1002","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5891-5615","authenticated-orcid":false,"given":"Mana","family":"Nishikawa","sequence":"first","affiliation":[{"name":"Department of Nephrology Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriaki","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Nephrology Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoko","family":"Kanzaki","sequence":"additional","affiliation":[{"name":"Department of Nephrology Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsunori","family":"Ikegami","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Fukuoka","sequence":"additional","affiliation":[{"name":"Department of General Medicine Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine Shigei Research Institute Hospital Okayama Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichiro","family":"Asano","sequence":"additional","affiliation":[{"name":"Department of Nephrology Kurashiki Central Hospital Kurashiki Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,2,21]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2008010098"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0031-6997(25)00067-5","article-title":"Excess magnesium","volume":"29","author":"Mordes JP","year":"1977","journal-title":"Pharmacol. 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