{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T19:39:14Z","timestamp":1780342754671,"version":"3.54.1"},"reference-count":10,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,4,19]],"date-time":"2019-04-19T00:00:00Z","timestamp":1555632000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>The effect of intra\u2010arterial infusion of fasudil hydrochloride in patients with post\u2010traumatic cerebral vasospasm remains unclear. Here we report a case of intra\u2010arterial infusion of fasudil hydrochloride for post\u2010traumatic cerebral vasospasm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 47\u2010year\u2010old man was transferred to our hospital with a fractured skull and traumatic subarachnoid hemorrhage. As rhinorrhea of cerebrospinal fluid had not improved, repair surgery was carried out on day 4. Aphasia appeared on day 13. Magnetic resonance imaging and angiography showed an ischemic region in the left temporal lobe and vasospasm of the left middle cerebral artery. We immediately carried out angiography and diagnosed severe vasospasm of the M1 region of the left middle cerebral artery. After placing a microcatheter into the proximal middle cerebral artery, we injected fasudil hydrochloride intra\u2010arterially. Vasospasm improved and aphasia resolved.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this case, intra\u2010arterial infusion of fasudil hydrochloride was effective against post\u2010traumatic cerebral vasospasm.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.420","type":"journal-article","created":{"date-parts":[[2019,4,20]],"date-time":"2019-04-20T04:11:46Z","timestamp":1555733506000},"page":"392-395","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Intra\u2010arterial infusion of fasudil hydrochloride to treat post\u2010traumatic cerebral vasospasm"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1705-8589","authenticated-orcid":false,"given":"Tomoaki","family":"Murakami","sequence":"first","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuichiro","family":"Kajikawa","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hajime","family":"Nakamura","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Nishida","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhiro","family":"Yoshimura","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoyuki","family":"Yoshihara","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Koichiro","family":"Tsuruzono","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akatsuki","family":"Wakayama","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka Neurological Institute Toyonaka City Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruhiko","family":"Kishima","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Osaka University Graduate School of Medicine Suita Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,4,19]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1219","article-title":"Cerebral vasospasm after traumatic brain injury: an update","volume":"81","author":"Perrein A","year":"2015","journal-title":"Minerva Anestesiol."},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1992.76.4.0571"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/415813"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1227\/01.NEU.0000249193.68904.B4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3171\/2012.4.JNS111549"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.7887\/jcns.11.777"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1998.88.2.0277"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354755"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.st2013-0149"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.50.7"}],"container-title":["Acute Medicine &amp; Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.420","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ams2.420","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.420","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T03:56:11Z","timestamp":1694318171000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,19]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/ams2.420"],"URL":"https:\/\/doi.org\/10.1002\/ams2.420","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"value":"2052-8817","type":"print"},{"value":"2052-8817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,19]]},"assertion":[{"value":"2018-11-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-03-19","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}