{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T01:51:44Z","timestamp":1792029104814,"version":"4.4.0"},"reference-count":12,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T00:00:00Z","timestamp":1559779200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2019,10]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>We divided patients treated with emergency surgery for pan\u2010peritonitis caused by colon perforation into the survival group and the death group based on outcome at postoperative day 30 and examined the prognostic factors for colon perforation.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>The prognostic factors for colon perforation in 76 consecutive patients who underwent emergency surgery at Kansai Medical University Hospital (Hirakata, Japan) from April 2011 to March 2017 were investigated based on outcome at postoperative day 30.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The average age of the 76 patients (41 men\/35 women) was 73\u00a0years, and the causative disease of colon perforation was malignant\/benign in 18\/58 cases, with ileocecal perforation site in 8 cases, ascending colon in 6, transverse colon in 2, descending colon in 4, sigmoid colon in 49, and rectum in 7. All patients received laparotomy with irrigation drainage, and 9 patients (11.8%) were dead at 30\u00a0days. Upon comparing the 67 survivors with the 9 dead patients, we recognized a significant difference on preoperative spread of ascites on computed tomography (<jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content>) (<jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.002) in univariate analysis and on acute disseminated intravascular coagulation (<jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content>) score (odds ratio 2.289; 95% confidence interval, 1.188\u20134.410; <jats:italic>P\u00a0<\/jats:italic>=<jats:italic>\u00a0<\/jats:italic>0.013) in multivariate analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In our hospital, the preoperative acute <jats:styled-content style=\"fixed-case\">DIC<\/jats:styled-content> score was found to be a prognostic factor for colon perforation accompanied by pan\u2010peritonitis. Appropriate evaluation of the spread of ascites on the preoperative <jats:styled-content style=\"fixed-case\">CT<\/jats:styled-content> might also help predict patient prognosis.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.429","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T07:29:02Z","timestamp":1559806142000},"page":"379-384","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["Study of the prognostic factor of the colon perforation case with the pan\u2010peritonitis that needed emergency surgery: a single\u2010center observational study"],"prefix":"10.1002","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3638-7708","authenticated-orcid":false,"given":"Fumiko","family":"Nakamura","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rintaro","family":"Yui","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arisa","family":"Muratsu","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kazuhito","family":"Sakuramoto","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Muroya","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hitoshi","family":"Ikegawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuyuki","family":"Kuwagata","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kansai Medical University Hirakata Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,6,6]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2014.03.021"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-013-1738-1"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10151-016-1506-7"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-015-0020-y"},{"key":"e_1_2_7_6_1","first-page":"1007","article-title":"SOFA score predicts postoperative outcome of patients with colorectal perforation","volume":"51","author":"Ochiai T","year":"2004","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_7_1","first-page":"430","article-title":"POSSUM is an optimal system for predicting mortality due to colorectal perforation","volume":"55","author":"Ishizuka M","year":"2008","journal-title":"Hepatogastroenterology"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v13.i23.3228"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000202209.42491.38"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1177\/107602960501100108"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000295317.97245.2D"},{"key":"e_1_2_7_12_1","first-page":"17","article-title":"Coagulopathy in disseminated intravascular coagulation due to abdominal sepsis: determination of prothrombin fragment 1\u00a0+\u00a02 and other markers","volume":"22","author":"Okamoto K","year":"1992","journal-title":"Haemostasis"},{"key":"e_1_2_7_13_1","first-page":"56","article-title":"Assessment of predictors of mortality and severity in patients with colorectal perforation","volume":"102","author":"Egashira A","year":"2011","journal-title":"Fukuoka Igaku Zasshi"}],"container-title":["Acute Medicine &amp; Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fams2.429","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.429","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ams2.429","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.429","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,10]],"date-time":"2023-09-10T03:56:05Z","timestamp":1694318165000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,6]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2019,10]]}},"alternative-id":["10.1002\/ams2.429"],"URL":"https:\/\/doi.org\/10.1002\/ams2.429","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"value":"2052-8817","type":"print"},{"value":"2052-8817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,6]]},"assertion":[{"value":"2018-11-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-07","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}