{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,30]],"date-time":"2026-08-30T08:52:43Z","timestamp":1788079963334,"version":"build-2784847793"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T00:00:00Z","timestamp":1607731200000},"content-version":"vor","delay-in-days":346,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:sec><jats:title>Background<\/jats:title><jats:p>There are two types of amiodarone\u2010induced thyrotoxicosis (AIT). Type 1 AIT is increased synthesis of thyroid hormone, whereas type 2 AIT is excess release of thyroid hormone due to a destructive thyroiditis. However, cases leading to amiodarone\u2010induced thyroid storm are rare.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case presentation<\/jats:title><jats:p>A 75\u2010year\u2010old man with a history of chronic heart failure, nonsustained ventricular tachycardia, and atrial fibrillation was treated with amiodarone from age 72. He was presented to the emergency department with edema of the legs and dyspnea on exertion for 3\u00a0weeks. He was diagnosed with thyroid storm associated with type 2 AIT on the basis of no pre\u2010existing thyroid disease and long\u2010term amiodarone administration without appropriate medical attention and thyroid function tests.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This case report suggests that amiodarone can cause not only AIT but also thyroid storm. Regular medical appointment and thyroid function tests can avoid this critical illness.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.616","type":"journal-article","created":{"date-parts":[[2020,12,12]],"date-time":"2020-12-12T09:57:57Z","timestamp":1607767077000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Thyroid storm associated with type 2 amiodarone\u2010induced thyrotoxicosis due to long\u2010term administration: a case report"],"prefix":"10.1002","volume":"7","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8072-6298","authenticated-orcid":false,"given":"Kiyoshi","family":"Takemoto","sequence":"first","affiliation":[{"name":"Division of Critical Care Medicine Nara Prefecture General Medical Center Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimon","family":"Takada","sequence":"additional","affiliation":[{"name":"Department of General Internal Medicine Nishinokyo Hospital Nara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,12,12]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"269","article-title":"Amiodarone\u2013induced thyroid dysfunction in clinical practice","volume":"10","author":"Ursella S","year":"2006","journal-title":"Eur. 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