{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:01:57Z","timestamp":1790740917971,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T00:00:00Z","timestamp":1620000000000},"content-version":"vor","delay-in-days":122,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>Skin and soft tissue infections are classified into cellulitis and necrotizing fasciitis, which are difficult to distinguish. Necrotizing fasciitis has a poor prognosis and requires immediate intensive care. The diagnostic gold standard is to incise the lesion to determine whether necrosis has reached the fascia. We aimed to show that these infections can be differentiated using near\u2010infrared spectroscopy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We describe two cases in an observational study about the utility of near\u2010infrared spectroscopy. Case 1 involved a 77\u2010year\u2010old man with a chief complaint of pain, redness, and swelling in the right lower leg for 1\u00a0week. Computed tomography of his legs showed no gas formation. Case 2 involved an 82\u2010year\u2010old man. He visited another hospital because of pain, redness, and swelling in the right thigh. Based on the X\u2010ray examination, necrotizing fasciitis was suspected, and he was transferred to our hospital.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>In Case 1, the regional oxygen saturation value was lower on the lesion side (41%) than on the healthy side (55%). We confirmed the depth of invasion by incision, leading to a diagnosis of necrotizing fasciitis. In Case 2, the thigh\u2019s regional oxygen saturation was higher on the affected side (76%) than on the healthy side (61%). An incision was made for diagnosis, but the fascia was not necrotized. Thus, we diagnosed cellulitis and provided conservative treatment using antibiotics.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Near\u2010infrared spectroscopy can be utilized to measure tissue blood flow, and it could be useful as a non\u2010invasive diagnostic tool for skin and soft tissue infections.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ams2.642","type":"journal-article","created":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T04:02:45Z","timestamp":1620014565000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Diagnosis of skin and soft tissue infections using near\u2010infrared spectroscopy"],"prefix":"10.1002","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4813-0173","authenticated-orcid":false,"given":"Marina","family":"Oi","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kitasato University School of Medicine Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8465-6274","authenticated-orcid":false,"given":"Takaaki","family":"Maruhashi","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kitasato University School of Medicine Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenichi","family":"Kumazawa","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Kitasato University Hospital Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saori","family":"Iwakawa","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Kitasato University Hospital Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaro","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kitasato University School of Medicine Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyunpei","family":"Wato","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Kitasato University Hospital Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuta","family":"Niimi","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Kitasato University Hospital Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Takeda","sequence":"additional","affiliation":[{"name":"Department of Plastic and Reconstructive Surgery Kitasato University Hospital Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasushi","family":"Asari","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kitasato University School of Medicine Sagamihara Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,5,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2009.04.006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200308000-00005"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000129486.35458.7D"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000002774"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3757\/jser.74.552"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex182"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13049\u2010014\u20100058\u2010y"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2017.11.029"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/GOX.0000000000002742"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2015.0678"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2004.03.022"},{"key":"e_1_2_6_13_1","first-page":"701","article-title":"An assessment of ischemic limbs using near\u2010infrared spectroscopy in patients with atherosclerotic occlusive disease","volume":"9","author":"Watanabe T","year":"2000","journal-title":"Jpn. J. Vasc. Surg."},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/1089253216644346"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/0267659118777670"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200703000-00009"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0885066617735270"}],"container-title":["Acute Medicine &amp; Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.642","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ams2.642","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.642","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T07:45:35Z","timestamp":1692603935000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/ams2.642"],"URL":"https:\/\/doi.org\/10.1002\/ams2.642","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"value":"2052-8817","type":"print"},{"value":"2052-8817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2020-12-28","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-05-03","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e642"}}