{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T07:51:37Z","timestamp":1753861897016,"version":"3.41.2"},"reference-count":9,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T00:00:00Z","timestamp":1726012800000},"content-version":"vor","delay-in-days":254,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine & Surgery"],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Direct reinfusion of pericardial blood during cardiac surgery triggers a systemic inflammatory response. Although various inflammatory mediators have been identified as triggers, the role of damage\u2010associated molecular patterns (DAMPs) remains poorly understood. Despite guidelines recommending against this practice owing to its harmful effects, it is sometimes used in emergencies.<\/jats:p><\/jats:sec>Case Presentation<\/jats:title>A 72\u2010year\u2010old man with atrial fibrillation and cerebral infarction developed cardiac tamponade during catheter ablation. He underwent pericardial drainage and direct blood reinfusion. He was transferred to our ICU, where he developed acute respiratory distress syndrome (ARDS) and disseminated intravascular coagulation (DIC). Despite aggressive management, the patient died 41\u2009days after admission.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>This case highlights severe adverse events following direct reinfusion of pericardial blood. These findings suggest a significant role for DAMPs in mediating these inflammatory responses. Direct reinfusion of pericardial drainage blood should be avoided during emergencies to prevent life\u2010threatening complications.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.70005","type":"journal-article","created":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T12:58:55Z","timestamp":1726059535000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Direct reinfusion of pericardial blood complications: A case of acute respiratory distress syndrome and disseminated intravascular coagulation"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-8929-0787","authenticated-orcid":false,"given":"Takuto","family":"Yasuda","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kasumi","family":"Satoh","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9329-0534","authenticated-orcid":false,"given":"Nobuhisa","family":"Hirasawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manabu","family":"Okuyama","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3733-3530","authenticated-orcid":false,"given":"Hajime","family":"Nakae","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Akita University Graduate School of Medicine Akita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,9,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.02.003"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2006.03.027"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)63358-9"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.107.4.1062"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10495-021-01663-3"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10051044"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1227751"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1160\/TH05-05-0316"},{"volume-title":"Cell Saver Elite+","year":"2017","author":"Haemonetics","key":"e_1_2_8_10_1"}],"container-title":["Acute Medicine & Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.70005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T10:48:19Z","timestamp":1735555699000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.70005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/ams2.70005"],"URL":"https:\/\/doi.org\/10.1002\/ams2.70005","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"type":"print","value":"2052-8817"},{"type":"electronic","value":"2052-8817"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2024-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70005"}}