{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:46:46Z","timestamp":1782460006585,"version":"3.54.5"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":176,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001691","name":"Japan Society for the Promotion of Science","doi-asserted-by":"publisher","award":["JP 21K09083"],"award-info":[{"award-number":["JP 21K09083"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp;amp; Surgery"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>\u201cHuman skin gas,\u201d the trace amounts of bio\u2010volatile gases emitted from the surface of human skin, contains a variety of biological information and can be used in diagnosing several diseases. Herein, we described a case of the identification of the causative agent in a patient with acute poisoning using human skin gas.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Presentation<\/jats:title>\n                    <jats:p>A 52\u2010year\u2010old man cut his wrists and neck and crashed his car into a tunnel wall. The patient informed the paramedics that he had taken paraquat dimethyl sulfate and was transported to our emergency medical center. Since paraquat was not found in the home, the skin gas was measured, and ortho\u2010dichlorobenzene was detected. An insecticide containing ortho\u2010dichlorobenzene was found in the home, and he was strongly suggested with ortho\u2010dichlorobenzene poisoning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The human skin gas assay was used to identify intoxicants and is useful for the diagnosis of poisoning.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ams2.70136","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:00:33Z","timestamp":1782457233000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A Case of Acute Poisoning Due to Ortho\u2010Dichlorobenzene Diagnosed Using Biological Volatile Gas Analysis"],"prefix":"10.1002","volume":"13","author":[{"given":"Eiji","family":"Kawamoto","sequence":"first","affiliation":[{"name":"Department of Emergency and Disaster Medicine Mie University Hospital  Tsu Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5875-7645","authenticated-orcid":false,"given":"Kazuo","family":"Umezawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Tokai University School of Medicine  Isehara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6048-7269","authenticated-orcid":false,"given":"Yoshika","family":"Sekine","sequence":"additional","affiliation":[{"name":"Department of Chemistry Tokai University School of Science  Hiratsuka Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsuya","family":"Hane","sequence":"additional","affiliation":[{"name":"Department of Emergency and Disaster Medicine Mie University Hospital  Tsu Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryo","family":"Esumi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Mie Chuo Medical Center  Tsu Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yohei","family":"Ieki","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Nagai Hospital  Tsu Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satomi","family":"Asai","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine Tokai University School of Medicine  Isehara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Tokai University School of Medicine  Isehara Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Jinno","sequence":"additional","affiliation":[{"name":"Emergency Medical Center, Kagawa University Hospital  Kita Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Kuroda","sequence":"additional","affiliation":[{"name":"Emergency Medical Center, Kagawa University Hospital  Kita Kagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Imai","sequence":"additional","affiliation":[{"name":"Department of Emergency and Disaster Medicine Mie University Hospital  Tsu Mie Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,26]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"crossref","first-page":"1360","DOI":"10.1080\/15563650.2020.1834219","article-title":"2019 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 37th Annual Report","volume":"58","author":"Gummin D. 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B, Analytical Technologies in the Biomedical and Life Sciences"},{"key":"e_1_2_10_6_1","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1081\/CI-120013506","article-title":"New Measurement of Hydrogen Gas and Acetone Vapor in Gases Emanating From Human Skin","volume":"30","author":"Naitoh K.","year":"2002","journal-title":"Instrumentation Science and Technology"},{"key":"e_1_2_10_7_1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jchromb.2016.06.021","article-title":"Measurement of 2\u2010Nonenal and Diacetyl Emanating From Human Skin Surface Employing Passive Flux Sampler\u2010GCMS System","volume":"1028","author":"Kimura K.","year":"2016","journal-title":"Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences"},{"key":"e_1_2_10_8_1","doi-asserted-by":"crossref","DOI":"10.1016\/j.rechem.2022.100502","article-title":"Development of a Wristband\u2010Type Wearable Device for the Colorimetric Detection of Ammonia Emanating From the Human Skin Surface","volume":"4","author":"Ikeda S.","year":"2022","journal-title":"Results in Chemistry"},{"issue":"4","key":"e_1_2_10_9_1","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1111\/j.1365-2133.2008.08748.x","article-title":"Analyses of Volatile Organic Compounds From Human Skin","volume":"159","author":"Gallagher M.","year":"2008","journal-title":"British Journal of Dermatology"},{"key":"e_1_2_10_10_1","doi-asserted-by":"crossref","first-page":"824","DOI":"10.3390\/metabo12090824","article-title":"The Human Skin Volatolome: A Systematic Review of Untargeted Mass Spectrometry Analysis","volume":"12","author":"Mitra A.","year":"2022","journal-title":"Metabolites"},{"key":"e_1_2_10_11_1","volume-title":"Initial Environmental Risk Assessment of Chemical Substances: O\u2010Dichlorobenzene","year":"2023"}],"container-title":["Acute Medicine &amp; Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.70136","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ams2.70136","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.70136","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T07:00:35Z","timestamp":1782457235000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.70136"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["10.1002\/ams2.70136"],"URL":"https:\/\/doi.org\/10.1002\/ams2.70136","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"value":"2052-8817","type":"print"},{"value":"2052-8817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"2024-11-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70136"}}