{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T07:51:39Z","timestamp":1753861899807,"version":"3.41.2"},"reference-count":27,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T00:00:00Z","timestamp":1638748800000},"content-version":"vor","delay-in-days":339,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of the current study was to evaluate the prevalence of coronavirus disease (COVID\u201019) in methanol\u2010poisoned patients admitted to two toxicology academic centers during the COVID\u201019 outbreak and determine their clinical features and chest\/brain computed tomography (CT) findings.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Methanol\u2010poisoned patients who had been referred during the COVID\u201019 pandemic were evaluated for signs and symptoms of COVID\u201019 by chest CT scans and\/or polymerase chain reaction test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 62 patients with confirmed methanol poisoning were enrolled in the study, with a median (interquartile range) age of 35 (28\u201344)\u2009years. Thirty\u2010nine (62.9%) survived. Nine (14.5%) were diagnosed to have COVID\u201019, of whom four survived. There was a significant correlation between COVID\u201019 disease and a history of alcohol consumption (<jats:italic>p<\/jats:italic>\u2009=\u20090.036; odds ratio 1.7; 95% confidence interval, 1.3\u20132.2). Univariate analysis showed significant differences between infected and noninfected patients regarding their urea and time for first and second hemodialysis sessions, as well as the duration of ethanol administration.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>In conclusion, during the pandemic, specific attention should be paid to patients with a history of alcohol ingestion and elevated creatinine, loss of consciousness, and severe acidosis as these signs\/symptoms could be present in both COVID\u201019 and methanol poisoning, making differentiation between the two challenging.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.715","type":"journal-article","created":{"date-parts":[[2021,12,6]],"date-time":"2021-12-06T12:00:38Z","timestamp":1638792038000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Prevalence of clinical and radiologic features in methanol\u2010poisoned patients with and without COVID\u201019 infection"],"prefix":"10.1002","volume":"8","author":[{"given":"Nasim","family":"Zamani","sequence":"first","affiliation":[{"name":"Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Department of Clinical Toxicology Loghman\u2010Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farzad","family":"Gheshlaghi","sequence":"additional","affiliation":[{"name":"Department of Clinical Toxicology Isfahan Clinical Toxicology Research Center School of Medicine Isfahan University of Medical Sciences Isfahan Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryam","family":"Haghighi\u2010Morad","sequence":"additional","affiliation":[{"name":"Department of Radiology Loghman\u2010Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hooman","family":"Bahrami\u2010Motlagh","sequence":"additional","affiliation":[{"name":"Department of Radiology Loghman\u2010Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilad","family":"Alavi Darazam","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Loghman\u2010Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9104-971X","authenticated-orcid":false,"given":"Seyed Kaveh","family":"Hadeiy","sequence":"additional","affiliation":[{"name":"Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca","family":"McDonald","sequence":"additional","affiliation":[{"name":"Institute of Psychiatry, Psychology and Neuroscience National Addiction Centre King\u2019s College London London UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4370-0544","authenticated-orcid":false,"given":"Hossein","family":"Hassanian\u2010Moghaddam","sequence":"additional","affiliation":[{"name":"Social Determinants of Health Research Center Shahid Beheshti University of Medical Sciences Tehran Iran"},{"name":"Department of Clinical Toxicology Loghman\u2010Hakim Hospital School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,6]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03259846"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.1081\/CLT-120006745"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0379-0738(02)00376-6"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.7326\/L18-0584"},{"key":"e_1_2_8_6_1","unstructured":"Iran (Islamic Republic of) Situation. Accessed on October 9 2021. Available from:https:\/\/covid19.who.int\/region\/emro\/country\/ir"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03140-w"},{"key":"e_1_2_8_8_1","unstructured":"https:\/\/per.euronews.com\/2020\/03\/27\/480\u2010die\u2010in\u2010iran\u2010due\u2010to\u2010alcohol\u2010poisonings. Accessed on July 10 2021"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1148\/ryct.2020200152"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13492"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medcli.2017.06.044"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2017.05.035"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1101\/2020.04.22.20075416"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.26300"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.03.005"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-14-1360"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-018-1135-3"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.03.017"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00038-020-01390-7"},{"key":"e_1_2_8_20_1","first-page":"105","article-title":"Expert recommendations for tracheal intubation in critically ill patients with noval Coronavirus Disease 2019","volume":"35","author":"Zuo MZ","year":"2020","journal-title":"Chin. Med. Sci. J."},{"key":"e_1_2_8_21_1","first-page":"344","article-title":"A brief review on toxic alcohols: management strategies","volume":"10","author":"Hassanian\u2010Moghaddam H","year":"2016","journal-title":"Iran J. Kidney Dis."},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2008.11.006"},{"key":"e_1_2_8_23_1","first-page":"737","article-title":"Imaging findings after methanol intoxication (cohort of 46 patients)","volume":"36","author":"Vaneckova M","year":"2015","journal-title":"Neuro. Endocrinol. Lett."},{"key":"e_1_2_8_24_1","first-page":"522","article-title":"Methanol poisoning: bilateral putaminal and cerebellar cortical lesions on CT and MR","volume":"15","author":"Chen JC","year":"1991","journal-title":"J. Comput. Assist. Tomogr."},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1600-0455.2003.00138.x"},{"key":"e_1_2_8_26_1","first-page":"61","article-title":"Risk factors for mortality in Asian Taiwanese patients with methanol poisoning","volume":"10","author":"Lee CY","year":"2014","journal-title":"Ther. Clin. Risk Mang."},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/10915810490506795"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-019-1404-0"}],"container-title":["Acute Medicine &amp; Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.715","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/ams2.715","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.715","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,21]],"date-time":"2023-08-21T11:38:53Z","timestamp":1692617933000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.715"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":27,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1002\/ams2.715"],"URL":"https:\/\/doi.org\/10.1002\/ams2.715","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"type":"print","value":"2052-8817"},{"type":"electronic","value":"2052-8817"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"2021-08-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-16","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e715"}}