{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,17]],"date-time":"2026-04-17T11:22:17Z","timestamp":1776424937150,"version":"3.51.2"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T00:00:00Z","timestamp":1644537600000},"content-version":"vor","delay-in-days":41,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aimed to investigate the association between level of impaired consciousness and severe hypothermia (&lt;28\u00b0C) and to evaluate the association between level of impaired consciousness and inhospital mortality among accidental hypothermia patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a multicenter retrospective study using the J\u2010Point registry database, which includes data regarding patients whose core body temperature was 35.0\u00b0C or less and who were treated as accidental hypothermia in emergency departments between April 1, 2011 and March 31, 2016. We estimated adjusted odds ratios of the level of impaired consciousness for severe hypothermia less than 28\u00b0C and inhospital mortality using a logistic regression model.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 505 of 572 patients in the J\u2010Point registry. Relative to mildly impaired consciousness (Glasgow Coma Scale [GCS] 13\u201315), the adjusted odds ratios for severe hypothermia less than 28\u00b0C were: moderate (GCS 9\u201312), 3.26 (95% confidence interval [CI], 1.69\u20136.25); and severe (GCS\u2009&lt;\u20099), 4.68 (95% CI, 2.40\u20139.14). Relative to mildly impaired consciousness (GCS 13\u201315), the adjusted odds ratios for inhospital mortality were: moderate (GCS9\u201312), 1.65 (95% CI, 0.95\u20132.88); and severe (GCS\u2009&lt;\u20099), 2.10 (95% CI, 1.17\u20133.78).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The level of impaired consciousness in patients with accidental hypothermia was associated with severe hypothermia and inhospital mortality.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ams2.730","type":"journal-article","created":{"date-parts":[[2022,2,11]],"date-time":"2022-02-11T13:19:50Z","timestamp":1644585590000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":5,"title":["Clinical relevance of impaired consciousness in accidental hypothermia: a Japanese multicenter retrospective study"],"prefix":"10.1002","volume":"9","author":[{"given":"Masahiro","family":"Fukuda","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Saiseikai Shiga Hospital Ritto Japan"},{"name":"Senri Critical Care Medical Center Saiseikai Senri Hospital Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Nozawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Saiseikai Shiga Hospital Ritto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2266-476X","authenticated-orcid":false,"given":"Yohei","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Japanese Red Cross Society Kyoto Daini Hospital Kyoto Japan"},{"name":"Department of Primary Care and Emergency Medicine Graduate School of Medicine Kyoto University Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Morita","sequence":"additional","affiliation":[{"name":"Senri Critical Care Medical Center Saiseikai Senri Hospital Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Ehara","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Japanese Red Cross Society Kyoto Daiichi Red Cross Hospital Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Miyamae","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Rakuwa\u2010kai Otowa Hospital Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Uji\u2010Tokushukai Medical Center Uji 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Medicine Graduate School of Medicine Osaka University Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tasuku","family":"Matsuyama","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kyoto Prefectural University of Medicine Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,2,11]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1114208"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/emermed-2017-207238","article-title":"Characteristics and outcomes of accidental hypothermia in Japan: the J\u2010Point registry","volume":"35","author":"Matsuyama T","year":"2018","journal-title":"Emerg. 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