{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:04:05Z","timestamp":1789441445569,"version":"build-2803163510"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2022,3,13]],"date-time":"2022-03-13T00:00:00Z","timestamp":1647129600000},"content-version":"vor","delay-in-days":71,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:sec><jats:title>Aim<\/jats:title><jats:p>Foreign body airway obstruction (FBAO) is a major public health concern worldwide for infants and older adults. This study determines the association between airway obstruction time and neurological outcomes to plan an effective response for patients with FBAO.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>This multicenter retrospective observational study was carried out among patients with life\u2010threatening FBAO in Japan over a period of 4 years. The duration of airway obstruction was calculated from the time of the accident to the time of foreign body removal. The study examined the relationship between airway obstruction time and outcome. The primary outcome was vegetative state or death at hospital discharge.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Among 119 patients, 68 were in the category of vegetative state or death. Logistic regression analysis showed that longer airway obstruction time (adjusted odds ratio 1.04; 95% confidence interval 1.01\u20131.07) was associated with vegetative state or death. When the cut\u2010off value was set at 10, the sensitivity was 0.88, the specificity 0.47, with the area under the curve 0.69. Using the other cut\u2010off value of 4\u2009min, the negative predictive value was 1.00.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Longer airway obstruction time was associated with vegetative state or death for patients with FBAO. The incidence of vegetative state or death increased when the airway obstruction time exceeded 10\u2009min. Meanwhile, 4\u2009min or less may be set as a target time for foreign body removal in order to prevent vegetative state or death and plan an effective response.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.741","type":"journal-article","created":{"date-parts":[[2022,3,14]],"date-time":"2022-03-14T03:09:19Z","timestamp":1647227359000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":42,"title":["Airway obstruction time and outcomes in patients with foreign body airway obstruction: multicenter observational choking investigation"],"prefix":"10.1002","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4305-2850","authenticated-orcid":false,"given":"Yutaka","family":"Igarashi","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7428-5625","authenticated-orcid":false,"given":"Tatsuya","family":"Norii","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine University of New Mexico  Albuquerque New Mexico USA"},{"name":"Department of Traumatology and Acute Critical Medicine Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim","family":"Sung\u2010Ho","sequence":"additional","affiliation":[{"name":"Senshu Trauma and Critical Care Center Rinku General Medical Center  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimpei","family":"Nagata","sequence":"additional","affiliation":[{"name":"Department of Clinical Epidemiology and Health Economics The University of Tokyo  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yudai","family":"Yoshino","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"},{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School Musashi Kosugi Hospital  Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takuro","family":"Hamaguchi","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riko","family":"Nagaosa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunichiro","family":"Nakao","sequence":"additional","affiliation":[{"name":"Department of Traumatology and Acute Critical Medicine Osaka University Graduate School of Medicine  Osaka Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Tagami","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"},{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School Musashi Kosugi Hospital  Kanagawa Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7409-704X","authenticated-orcid":false,"given":"Shoji","family":"Yokobori","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Nippon Medical School  Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,13]]},"reference":[{"key":"e_1_2_8_2_1","unstructured":"National Safety Council.Injury Facts in 2018. 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