{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:28:47Z","timestamp":1791646127949,"version":"4.3.4"},"reference-count":10,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T00:00:00Z","timestamp":1685404800000},"content-version":"vor","delay-in-days":149,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p><jats:italic>Capnocytophaga canimorsus<\/jats:italic> is an oral commensal bacteria in dogs and may cause severe infection following a dog bite. This is a case of fatal <jats:italic>C. canimorsus<\/jats:italic> sepsis with acute infectious purpura fulminans (AIPF) in a healthy patient with splenic hypoplasia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Case Presentation<\/jats:title><jats:p>A healthy 49\u2010year\u2010old man was admitted to the intensive care unit (ICU) for septic shock and AIPF 4\u2009days after a dog bite to his mouth. Computed tomography revealed a small spleen measuring 53\u2009cm<jats:sup>3<\/jats:sup> but no other source of infection. Despite intensive care, the patient died of multiple organ failure and progressive shock on the fifth ICU day. Polymerase chain reaction of blood samples identified the <jats:italic>C. canimorsus<\/jats:italic> gene on a later day.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p><jats:italic>Capnocytophaga canimorsus<\/jats:italic> from dog bites may cause fatal AIPF. Splenic hypoplasia and bite wounds in well\u2010perfused areas such as the oral cavity are possible risk factors for sepsis. All dog bites should warrant medical attention.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.849","type":"journal-article","created":{"date-parts":[[2023,5,30]],"date-time":"2023-05-30T08:59:18Z","timestamp":1685437158000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Fatal case of <i>Capnocytophaga<\/i> sepsis from a dog bite in a patient with splenic hypoplasia"],"prefix":"10.1002","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3985-5589","authenticated-orcid":false,"given":"Natsuki","family":"Kondo","sequence":"first","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"},{"name":"Department of Emergency Medicine Koga Community Hospital  Yaizu Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yosuke","family":"Matsumura","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7212-418X","authenticated-orcid":false,"given":"Takuya","family":"Sugiyama","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaya","family":"Miyahara","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ai","family":"Imamura","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Kasahara","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Nagashima","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noriyuki","family":"Hanaoka","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naohiko","family":"Fujiyoshi","sequence":"additional","affiliation":[{"name":"Department of Intensive Care Medicine Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shin","family":"Inaba","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Chiba Emergency Medical Center  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2023,5,30]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901143400202"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu296"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/23.1.71"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.27.2.231-235.1989"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2010.01.001"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/23744235.2019.1687933"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/ams2.204"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-2769-y"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2009.08.013"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.00249-17"}],"container-title":["Acute Medicine &amp; 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