{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T06:06:35Z","timestamp":1773381995782,"version":"3.50.1"},"reference-count":6,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T00:00:00Z","timestamp":1707091200000},"content-version":"vor","delay-in-days":35,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine & Surgery"],"published-print":{"date-parts":[[2024,1]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Kounis syndrome (KS) is an underdiagnosed disease. The management of the disease remains elusive because of its infrequency.<\/jats:p><\/jats:sec>Case Presentation<\/jats:title>A 78\u2010year\u2010old man with anaphylactic shock was admitted to our hospital 2\u2009h after multiple bee stings. After recovering from an anaphylactic reaction, he presented with chest pain with ST elevation. We diagnosed him with KS. After a continuous intravenous infusion of vasodilators, his chest pain and ST elevation improved. However, chest pain with ST\u2010segment elevation recurred the next day. Coronary angiography revealed severe stenosis in the middle left anterior descending coronary artery, and drug\u2010eluting stents were implanted. The patient was discharged on foot after treatment for heart failure.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>KS, in which anaphylaxis and acute coronary syndrome occur simultaneously, can recur repeatedly after an initial anaphylactic reaction; however, it could be delayed or it could present simultaneously with the anaphylactic reaction. Therefore, long\u2010term observation is important.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.908","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T07:28:47Z","timestamp":1707290927000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["A case of repeated Kounis syndrome after anaphylactic shock: A note for disease management"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5562-115X","authenticated-orcid":false,"given":"Satoshi","family":"Kawaguchi","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatsuki","family":"Kuroshima","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryo","family":"Namba","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Satou","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riku","family":"Kashiwagi","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Abe","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3779-6703","authenticated-orcid":false,"given":"Motoi","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Asahikawa Medical University Asahikawa Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2024,2,5]]},"reference":[{"key":"e_1_2_9_2_1","first-page":"294","article-title":"Kounis syndrome: a clinical entity penetrating from pediatrics to geriatrics","volume":"5","author":"Giovannini M","year":"2020","journal-title":"J Geriatr Cardiol"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1515\/cclm-2016-0010"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2017.01.124"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2013.01.062"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/ams2.729"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s43044-021-00233-x"}],"container-title":["Acute Medicine & Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ams2.908","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,30]],"date-time":"2024-12-30T10:46:42Z","timestamp":1735555602000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ams2.908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,1]]}},"alternative-id":["10.1002\/ams2.908"],"URL":"https:\/\/doi.org\/10.1002\/ams2.908","archive":["Portico"],"relation":{},"ISSN":["2052-8817","2052-8817"],"issn-type":[{"value":"2052-8817","type":"print"},{"value":"2052-8817","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-10-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-11-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-02-05","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e908"}}