{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T07:51:59Z","timestamp":1753861919868,"version":"3.41.2"},"reference-count":23,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"vor","delay-in-days":135,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Acute Medicine &amp; Surgery"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>Hypothermia is associated with poor prognosis in patients with sepsis. However, no studies have explored the correlation between the severity of hypothermia and prognosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Using data from the Japanese accidental hypothermia network registry (J\u2010Point registry), we examined adult patients aged \u226518\u2009years with infectious diseases whose initial body temperature was \u226435\u00b0C from April 1, 2011 to March 31, 2016, in 12 centers. Patients were divided into three groups according to their body temperature: Tertile 1 (T1) (32.0\u201335.0\u00b0C), Tertile 2 (T2) (28.0\u201331.9\u00b0C), and Tertile 3 (T3) (&lt;28.0\u00b0C). In\u2010hospital mortality was employed as a metric to assess outcomes. We conducted a multivariate logistic regression analysis to investigate the relationship between the three categories and the occurrence of in\u2010hospital mortality.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 572 patients were registered, and 170 eligible patients were identified. Of these patients, 55 were in T1 (32.0\u201335.0\u00b0C), 76 in T2 (28.0\u201331.9\u00b0C), and 39 in T3 (&lt;28.0\u00b0C) groups. The overall in\u2010hospital mortality rate in accidental hypothermia (AH) patients with infectious diseases was 34.1%. The in\u2010hospital mortality rates in the T1, T2, and T3 groups were 34.5%, 36.8%, and 28.2%, respectively. The multivariable analysis demonstrated no significant differences regarding in\u2010hospital mortality among the three groups (T2 vs. T1, adjusted odds ratio [OR]: 1.29; 95% confidence interval [CI]: 0.58\u20132.89 and T3 vs. T1, adjusted OR: 0.83; 95% CI: 0.30\u20132.31).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In this multicenter retrospective observational study, hypothermia severity was not associated with in\u2010hospital mortality in AH patients with infectious diseases.<\/jats:p><\/jats:sec>","DOI":"10.1002\/ams2.964","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T05:28:36Z","timestamp":1715837316000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Association between the severity of hypothermia and in\u2010hospital mortality in patients with infectious diseases: The <scp>J\u2010Point<\/scp> registry"],"prefix":"10.1002","volume":"11","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-2562-4166","authenticated-orcid":false,"given":"Tadaharu","family":"Shiozumi","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine Kyoto Prefectural University of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuki","family":"Miyamoto","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kyoto Prefectural University of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sachiko","family":"Morita","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Senri Critical Care Medical Center, Saiseikai Senri Hospital  Suita Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Naoki","family":"Ehara","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Japanese Red Cross Kyoto Daiichi Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Miyamae","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Rakuwa\u2010kai Otowa Hospital  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2266-476X","authenticated-orcid":false,"given":"Yohei","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Japanese Red Cross Society Kyoto Daini Red Cross Hospital  Kyoto Japan"},{"name":"Health Services and Systems Research, Duke\u2010NUS Medical School National University of Singapore  Singapore City Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takaaki","family":"Jo","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Uji\u2010Tokushukai Medical Center  Uji Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasuyuki","family":"Sumida","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Rakuwa\u2010kai Otowa Hospital  Kyoto Japan"},{"name":"Department of Emergency Medicine North Medical Center, Kyoto Prefectural University of Medicine  Yosa\u2010Gun Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3680-2083","authenticated-orcid":false,"given":"Nobunaga","family":"Okada","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kyoto Prefectural University of Medicine  Kyoto Japan"},{"name":"Department of Emergency Medicine Japanese Red Cross Kyoto Daiichi Hospital  Kyoto Japan"},{"name":"Department of Emergency and Critical Care Medicine National Hospital Organization, Kyoto Medical Center  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0734-4047","authenticated-orcid":false,"given":"Makoto","family":"Watanabe","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Kyoto Prefectural University of Medicine  Kyoto Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Nozawa","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Saiseikai Shiga Hospital  Ritto Japan"},{"name":"Department of Emergency Medicine Shiga General Hospital  Moriyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayumu","family":"Tsuruoka","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine Kidney and Cardiovascular Center, Kyoto min\u2010Iren Chuo Hospital  Kyoto Japan"},{"name":"Department of Emergency and Critical Care Medicine Emergency and Critical Care Medical Center, Osaka City General Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Fujimoto","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Yodogawa Christian Hospital  Osaka Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiki","family":"Okumura","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine Fukuchiyama City Hospital  Fukuchiyama Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-0580","authenticated-orcid":false,"given":"Tetsuhisa","family":"Kitamura","sequence":"additional","affiliation":[{"name":"Department of Social and Environmental Medicine, Division of Environmental Medicine and Population Sciences Graduate School of Medicine, Osaka University  Suita 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