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In this study, we quantified the activity of this network in carriers of other dystonia mutations to determine whether this functional abnormality is linked to genotype. The findings suggest that the DYT1 metabolic topography is not genotype specific and may be present in carriers of other dystonia mutations.<\/jats:p>","DOI":"10.1002\/ana.10418","type":"journal-article","created":{"date-parts":[[2002,12,2]],"date-time":"2002-12-02T13:54:44Z","timestamp":1038837284000},"page":"853-856","source":"Crossref","is-referenced-by-count":107,"title":["Primary dystonia: Is abnormal functional brain architecture linked to genotype?"],"prefix":"10.1002","volume":"52","author":[{"given":"Maja","family":"Tros\u0306t","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maren","family":"Carbon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yilong","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Raymond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc J.","family":"Mentis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"Moeller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan B.","family":"Bressman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Eidelberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2002,11,22]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.50.5_Suppl_5.S1"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(01)00350-6"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440304"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/118.6.1473"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.5.673"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410420421"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf090"},{"key":"e_1_2_6_9_2","first-page":"1264","article-title":"Reproducibility of regional metabolic covariance patterns: comparison of four populations","volume":"40","author":"Moeller JR","year":"1999","journal-title":"J Nucl Med"},{"key":"e_1_2_6_10_2","volume-title":"MRI atlas of the human cerebellum","author":"Schmahmann JD","year":"2000"},{"key":"e_1_2_6_11_2","first-page":"378","article-title":"Assessment of disease severity in parkinsonism with fluorine\u201018\u2010 fluorodeoxyglucose and PET","volume":"36","author":"Eidelberg D","year":"1995","journal-title":"J Nucl Med"},{"key":"e_1_2_6_12_2","first-page":"S131","article-title":"Physiology of hypokinetic and hyperkinetic movement disorders: model for dyskinesia","volume":"47","author":"Vitek JL","year":"2000","journal-title":"Ann Neurol"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410440302"},{"key":"e_1_2_6_14_2","first-page":"A203","article-title":"Brain networks subserving motor sequence learning in DYT1 gene carriers","volume":"58","author":"Carbon M","year":"2002","journal-title":"Neurology"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)02410-7"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(96)80024-9"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.10418","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.10418","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T04:40:51Z","timestamp":1696999251000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.10418"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,11,22]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2002,12]]}},"alternative-id":["10.1002\/ana.10418"],"URL":"https:\/\/doi.org\/10.1002\/ana.10418","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[2002,11,22]]}}}