{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T07:24:32Z","timestamp":1771053872054,"version":"3.50.1"},"reference-count":20,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,3,24]],"date-time":"2003-03-24T00:00:00Z","timestamp":1048464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[2003,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Striatal dysfunction is thought to underlie many dystonias. We used [<jats:sup>123<\/jats:sup>I]iodobenzovesamicol single\u2010photon emission computed tomography imaging to determine the density of cholinergic terminals in the striatum and other brain regions in 13 subjects with idiopathic cervical dystonia. Striatal [<jats:sup>131<\/jats:sup>I]iodobenzovesamicol binding was reduced. These results support a role for striatal dysfunction in idiopathic dystonias and suggest diminished striatal cholinergic interneuron density in cervical dystonia. Ann Neurol 2003;53:528\u2013532<\/jats:p>","DOI":"10.1002\/ana.10527","type":"journal-article","created":{"date-parts":[[2003,3,25]],"date-time":"2003-03-25T11:59:50Z","timestamp":1048593590000},"page":"528-532","source":"Crossref","is-referenced-by-count":29,"title":["Diminished striatal [<sup>123<\/sup>I]iodobenzovesamicol binding in idiopathic cervical dystonia"],"prefix":"10.1002","volume":"53","author":[{"given":"Roger L.","family":"Albin","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donna","family":"Cross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wayne T.","family":"Cornblath","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John A.","family":"Wald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristine","family":"Wernette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kirk A.","family":"Frey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Minoshima","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,3,24]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/121.4.547"},{"key":"e_1_2_6_3_2","first-page":"53","article-title":"Symptomatic dystonias associated with structural brain lesions: report of 16 cases","volume":"20","author":"Kostic VS","year":"1996","journal-title":"Can J Neurol Sci"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/108.2.463"},{"key":"e_1_2_6_5_2","first-page":"113","article-title":"Clinicopathological correlation in symptomatic dystonia","volume":"50","author":"Obeso JA","year":"1988","journal-title":"Adv Neurol"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.7.650"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-200208000-00014"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.17-02-00843.1997"},{"key":"e_1_2_6_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.51.3.819"},{"key":"e_1_2_6_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awf279"},{"key":"e_1_2_6_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.52.2.291"},{"key":"e_1_2_6_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.3.691"},{"key":"e_1_2_6_13_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.8091209"},{"key":"e_1_2_6_14_2","first-page":"405","article-title":"In vivo mapping of cholinergic neurons in the human brain using SPECT and IBVM","volume":"35","author":"Kuhl DE","year":"1994","journal-title":"J Nucl Med"},{"key":"e_1_2_6_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410400309"},{"key":"e_1_2_6_16_2","doi-asserted-by":"publisher","DOI":"10.1109\/42.563664"},{"key":"e_1_2_6_17_2","first-page":"695","article-title":"Expression of the vesicular acetylcholine transporter is unaltered by pharmacological interventions in cholinergic transmission","volume":"23","author":"Bianchi MT","year":"1997","journal-title":"Soc Neurosci Abstr"},{"key":"e_1_2_6_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(95)00594-3"},{"key":"e_1_2_6_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.58.7.1013"},{"key":"e_1_2_6_20_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-06-03969.1994"},{"key":"e_1_2_6_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)00627-X"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.10527","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.10527","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,11]],"date-time":"2023-10-11T21:24:56Z","timestamp":1697059496000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.10527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3,24]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,4]]}},"alternative-id":["10.1002\/ana.10527"],"URL":"https:\/\/doi.org\/10.1002\/ana.10527","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,3,24]]}}}