{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T02:15:21Z","timestamp":1774923321500,"version":"3.50.1"},"reference-count":7,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2003,9,11]],"date-time":"2003-09-11T00:00:00Z","timestamp":1063238400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Spanish Minister of Health","award":["FIS 00\/0797"],"award-info":[{"award-number":["FIS 00\/0797"]}]},{"name":"FUNDISMUN Foundation"},{"name":"NIH","award":["NS11766"],"award-info":[{"award-number":["NS11766"]}]},{"name":"NIH","award":["POIHD-32062"],"award-info":[{"award-number":["POIHD-32062"]}]},{"DOI":"10.13039\/100005202","name":"Muscular Dystrophy Association","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100005202","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Department of Neurological Sciences and Vision, University of Verona, Italy"},{"name":"Department of Neurosciences, University of Pisa, Italy"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In 2002, paternal inheritance of muscle mitochondrial DNA (mtDNA) was reported in a patient with exercise intolerance and a mitochondrial DNA (mtDNA) mutation restricted to skeletal muscle. To evaluate whether paternal inheritance is a common phenomenon, we studied 10 sporadic patients with skeletal muscle\u2010restricted mtDNA mutations: five harbored mtDNA point mutations in protein\u2010coding genes and five had single mtDNA deletions. We performed haplotype analysis and direct sequencing of the hypervariable regions 1 and 2 of the D\u2010loop in muscle and blood from the patients and, when available, in blood from their parents. We did not observe paternal inheritance in any of our patients.<\/jats:p>","DOI":"10.1002\/ana.10709","type":"journal-article","created":{"date-parts":[[2003,9,26]],"date-time":"2003-09-26T08:39:33Z","timestamp":1064565573000},"page":"524-526","source":"Crossref","is-referenced-by-count":54,"title":["Lack of paternal inheritance of muscle mitochondrial DNA in sporadic mitochondrial myopathies"],"prefix":"10.1002","volume":"54","author":[{"given":"Massimiliano","family":"Filosto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelangelo","family":"Mancuso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristofol","family":"Vives\u2010Bauza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maya R.","family":"Vil\u00e0","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara","family":"Shanske","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michio","family":"Hirano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antoni L.","family":"Andreu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"DiMauro","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2003,9,11]]},"reference":[{"key":"e_1_2_6_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020350"},{"key":"e_1_2_6_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199909303411404"},{"key":"e_1_2_6_4_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.55.5.644"},{"key":"e_1_2_6_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/07853890109002099"},{"key":"e_1_2_6_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/genetics\/144.4.1835"},{"key":"e_1_2_6_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/290457a0"},{"key":"e_1_2_6_8_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.10.4542"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.10709","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.10709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,29]],"date-time":"2023-09-29T04:50:28Z","timestamp":1695963028000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.10709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9,11]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2003,10]]}},"alternative-id":["10.1002\/ana.10709"],"URL":"https:\/\/doi.org\/10.1002\/ana.10709","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9,11]]}}}