{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T20:08:27Z","timestamp":1778098107842,"version":"3.51.4"},"reference-count":20,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2001,8,6]],"date-time":"2001-08-06T00:00:00Z","timestamp":997056000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[2001,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Ocular flutter is a rare horizontal eye movement disorder characterised by rapid saccadic oscillations. It has been hypothesised that it is caused by loss of \u201cpause\u201d neuronal inhibition of \u201cburst\u201d neuron function in the paramedian pontine reticular formation (PPRF); however there have been no imaging studies confirming such anatomical localisation. We report the case of a woman with an acute attack of multiple sclerosis associated both with ocular flutter and a circumscribed pontine lesion, mainly involving the PPRF on magnetic resonance imaging. As she recovered from the attack, both the midline pontine lesion and the ocular flutter dramatically improved. This case is the first clear evidence that at least some cases of ocular flutter are due to lesions involving the PPRF.<\/jats:p>","DOI":"10.1002\/ana.1140","type":"journal-article","created":{"date-parts":[[2002,8,25]],"date-time":"2002-08-25T19:58:07Z","timestamp":1030305487000},"page":"413-416","source":"Crossref","is-referenced-by-count":54,"title":["Ocular flutter associated with a localized lesion in the paramedian pontine reticular formation"],"prefix":"10.1002","volume":"50","author":[{"given":"Fred","family":"Schon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy L.","family":"Hodgson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dominic","family":"Mort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher","family":"Kennard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2001,8,6]]},"reference":[{"key":"e_1_2_5_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.1954.00920040324006"},{"key":"e_1_2_5_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s001150050173"},{"key":"e_1_2_5_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050088"},{"key":"e_1_2_5_5_2","first-page":"417","article-title":"Post malaria cerebellar ataxia and ocular flutter: report of two cases","volume":"7","author":"Idris MNA","year":"1999","journal-title":"East Afr Med J"},{"key":"e_1_2_5_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1700809"},{"key":"e_1_2_5_7_2","first-page":"469","article-title":"An autopsied case of purulent meningitis associated with ocular flutter","volume":"50","author":"Orimo S","year":"1998","journal-title":"Brain Nerve"},{"key":"e_1_2_5_8_2","volume-title":"Cranial neuroimaging and clinical neuroanatomy","author":"Kretschmann HJ","year":"1992"},{"key":"e_1_2_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(98)00151-1"},{"key":"e_1_2_5_10_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410050502"},{"key":"e_1_2_5_11_2","first-page":"95","article-title":"Voluntary saccadic oscilations, resembling ocular flutter and opsoclonus","volume":"14","author":"Yee RD","year":"1994","journal-title":"J Neuroophthamal"},{"key":"e_1_2_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410190315"},{"key":"e_1_2_5_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.902670302"},{"key":"e_1_2_5_14_2","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1996.75.6.2229"},{"key":"e_1_2_5_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/110.6.1699"},{"key":"e_1_2_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410360615"},{"key":"e_1_2_5_17_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/88.3.449"},{"key":"e_1_2_5_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1979.00500370081022"},{"key":"e_1_2_5_19_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00235785"},{"key":"e_1_2_5_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.53.3.200"},{"key":"e_1_2_5_21_2","doi-asserted-by":"publisher","DOI":"10.3109\/01658109609009668"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.1140","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.1140","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,19]],"date-time":"2023-11-19T12:59:27Z","timestamp":1700398767000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.1140"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8,6]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["10.1002\/ana.1140"],"URL":"https:\/\/doi.org\/10.1002\/ana.1140","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,8,6]]}}}