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We investigated microvascular territories of the lenticulostriate arteries, the recurrent artery of Heubner, the anterior choroidal artery, and striate branches of the anterior cerebral and anterior communicating arteries in perfusion\u2010fixed human brains by simultaneous injection of fluorescent dyes and a radio\u2010opaque substance in 5% gelatin. Territories were defined by ultraviolet illumination of dye and high\u2010resolution mammography of radio\u2010opaque substance. Brains were sectioned coplanar with the Talairach proportional grid system and vascular data were plotted, allowing for application to any human brain. The data suggest first that the lenticulostriate artery, recurrent artery of Heubner, and anterior choroidal artery supply distinct territories of the basal ganglia with minimal overlap and sparse anastomoses between major penetrating vessels. Individual territories are spatially consistent across brains and match the extent of major\/minor infarcts. Second, branching patterns of parental, second\u2010, and third\u2010order vessels leading to circumscribed terminal vascular beds could account structurally for \u201clacunar\u201d infarcts. Ann Neurol 2005<\/jats:p>","DOI":"10.1002\/ana.20505","type":"journal-article","created":{"date-parts":[[2005,5,18]],"date-time":"2005-05-18T00:46:33Z","timestamp":1116377193000},"page":"18-30","source":"Crossref","is-referenced-by-count":88,"title":["Tertiary microvascular territories define lacunar infarcts in the basal ganglia"],"prefix":"10.1002","volume":"58","author":[{"given":"Joel A.","family":"Feekes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih\u2010Wei","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Chaloupka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin 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