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All patients underwent\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010FP\u2010CIT SPECT and\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG myocardial scintigraphy within a few weeks of clinical diagnosis. All diagnoses at each center were agreed upon by the local clinician and an independent expert, both unaware of imaging data, and re\u2010evaluated after 12 months. Each image was visually classified as either normal or abnormal by 3 independent nuclear physicians blinded to patients' clinical data.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, sensitivity and specificity to DLB were respectively 93% and 100% for\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG myocardial scintigraphy, and 90% and 76% for\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010FP\u2010CIT SPECT. Lower specificity of striatal compared to myocardial imaging was due to decreased\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010FP\u2010CIT uptake in 7 non\u2010DLB subjects (3 with concomitant parkinsonism) who had normal\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG myocardial uptake. Notably, in our non\u2010DLB group, myocardial imaging gave no false\u2010positive readings even in those subjects (n\u2009=\u20097) with concurrent medical illnesses (diabetes and\/or heart disease) supposed to potentially interfere with\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG uptake.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010FP\u2010CIT SPECT and\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG myocardial scintigraphy have similar sensitivity for detecting DLB, but the latter appears to be more specific for excluding non\u2010DLB dementias, especially when parkinsonism is the only \u201ccore feature\u201d exhibited by the patient. Our data also indicate that the potential confounding effects of diabetes and heart disease on\n                      <jats:sup>123<\/jats:sup>\n                      I\u2010MIBG myocardial scintigraphy results might have been overestimated. Ann Neurol 2016;80:368\u2013378\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ana.24717","type":"journal-article","created":{"date-parts":[[2016,7,11]],"date-time":"2016-07-11T20:06:51Z","timestamp":1468267611000},"page":"368-378","source":"Crossref","is-referenced-by-count":54,"title":["<sup>123<\/sup>\n                    I\u20102\u03b2\u2010carbomethoxy\u20103\u03b2\u2010(4\u2010iodophenyl)\u2010\n                    <i>N<\/i>\n                    \u2010(3\u2010fluoropropyl) nortropane single photon emission computed tomography and\n                    <sup>123<\/sup>\n                    I\u2010metaiodobenzylguanidine myocardial scintigraphy in differentiating dementia with lewy bodies from other dementias: A comparative study"],"prefix":"10.1002","volume":"80","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2171-1720","authenticated-orcid":false,"given":"Pietro","family":"Tiraboschi","sequence":"first","affiliation":[{"name":"Division of Neurology V\/Neuropathology, Scientific Institute for Research, Hospitalization, and Care (IRCCS), Foundation \u201cCarlo Besta\u201d Neurological Institute Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angelo","family":"Corso","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Sant'Anna Hospital Como Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo Paolo","family":"Guerra","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine Poliambulanza Foundation Brescia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Nobili","sequence":"additional","affiliation":[{"name":"Department of Neuroscience University of Genoa Genoa Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arnoldo","family":"Piccardo","sequence":"additional","affiliation":[{"name":"Nuclear Medicine Unit, Department of Diagnostic Imaging E. 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