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Patients included if &gt;3\u2009years old, had 3D pre\u2010operative T1 magnetic resonance imaging (MRI; 1.5 or 3\u00a0T) with radiologic or histopathologic FCD after surgery. Images processed using the MELD protocol, masked with 3D regions\u2010of\u2010interest (ROI), and co\u2010registered to fsaverage_sym (symmetric template). FCDs were then co\u2010localized to 1 of 7 distributed functional cortical networks. Negative binomial regression evaluated effect of FCD size, network, histology, and sulcal depth on age of epilepsy onset. From this model, predictive age of epilepsy onset was calculated for each network.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Three hundred eighty\u2010eight patients had median age seizure onset 5\u2009years (interquartile range [IQR]\u00a0=\u00a03\u201311 years), median age at pre\u2010operative scan 18\u2009years (IQR\u00a0=\u00a011\u201328\u2009years). FCDs co\u2010localized to the following networks: limbic (90), default mode (87), somatomotor (65), front parietal control (52), ventral attention (32), dorsal attention (31), and visual (31). Larger lesions were associated with younger age of onset (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.01); age of epilepsy onset was associated with dominant network (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.04) but not sulcal depth or histology. Sensorimotor networks had youngest onset; the limbic network had oldest age of onset (<jats:italic>p<\/jats:italic> values\u2009&lt;0.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Interpretation<\/jats:title><jats:p>FCD co\u2010localization to distributed functional cortical networks is associated with age of epilepsy onset: sensory neural networks (somatomotor and visual) with earlier onset, and limbic latest onset. These variations may reflect developmental differences in synaptic\/white matter maturation or network activation and may provide a biological basis for age\u2010dependent epilepsy onset expression. 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