{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:27:21Z","timestamp":1786976841392,"version":"build-2736575974"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T00:00:00Z","timestamp":1732665600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM21\/00057"],"award-info":[{"award-number":["CM21\/00057"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM21\/00101"],"award-info":[{"award-number":["CM21\/00101"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CM23\/00002"],"award-info":[{"award-number":["CM23\/00002"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["INT23\/00066"],"award-info":[{"award-number":["INT23\/00066"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["JR21\/00060"],"award-info":[{"award-number":["JR21\/00060"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI22\/00387"],"award-info":[{"award-number":["PI22\/00387"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze long\u2010term clinical and biomarker features of anti\u2010contactin\u20101 (CNTN1) autoimmune nodopathy (AN).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Patients with anti\u2010CNTN1\n                      <jats:sup>+<\/jats:sup>\n                      autoimmune nodopathy detected in our laboratory from which clinical information was available were included. Clinical features and treatment response were retrospectively collected. Autoantibody, serum neurofilament light chain (sNfL), and serum CNTN1 levels (sCNTN1) were analyzed at baseline and follow up.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 31 patients were included. Patients presented with progressive sensory motor neuropathy (76.7%) with proximal (74.2%) and distal involvement (87.1%), ataxia (71.4%), and severe disability (median INCAT at nadir of 8). A total of 11 patients (35%) showed kidney involvement. Most patients (97%) received intravenous immunoglobulin, but only 1 achieved remission with intravenous immunoglobulin. A total of 22 patients (71%) received corticosteroids, and 3 of them (14%) did not need further treatments. Rituximab was effective in 21 of 22 patients (95.5%), with most of them (72%) receiving a single course. Four patients (12.9%) relapsed after a median follow up of 25\u2009months after effective treatment (12\u201348\u2009months). Anti\u2010CNTN1 titers correlated with clinical scales at sampling and were negative after treatment in all patients, but 1 (20\/21). sNfL levels were significantly higher and sCNTN1 significantly lower in anti\u2010CNTN1\n                      <jats:sup>+<\/jats:sup>\n                      patients than in healthy controls (sNfL: 135.9\u2009pg\/ml vs 7.48\u2009pg\/ml, sCNTN1: 25.03\u2009pg\/ml vs 22,186\u2009pg\/ml,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.0001). Both sNfL and sCNTN1 returned to normal levels after successful treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>\n                      Patients with anti\u2010CNTN1\n                      <jats:sup>+<\/jats:sup>\n                      autoimmune nodopathy have a characteristic clinical profile. Clinical and immunological relapses are infrequent after successful treatment, suggesting that continuous treatment is unnecessary. Anti\u2010CNTN1 antibodies, sNfL, and sCNTN1 levels are useful to monitor disease status in these patients. ANN NEUROL 2025;97:529\u2013541\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ana.27142","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T05:15:36Z","timestamp":1732684536000},"page":"529-541","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Long\u2010Term Follow Up in Anti\u2010Contactin\u20101 Autoimmune Nodopathy"],"prefix":"10.1002","volume":"97","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9850-8504","authenticated-orcid":false,"given":"Marta","family":"Caballero\u2010\u00c1vila","sequence":"first","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1553-2224","authenticated-orcid":false,"given":"Lorena","family":"Mart\u00edn\u2010Aguilar","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7336-4305","authenticated-orcid":false,"given":"Elba","family":"Pascual\u2010Go\u00f1i","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milou R.","family":"Michael","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marleen J.A.","family":"Koel\u2010Simmelink","sequence":"additional","affiliation":[{"name":"Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5769-1100","authenticated-orcid":false,"given":"Romana","family":"H\u00f6ftberger","sequence":"additional","affiliation":[{"name":"Division of Neuropathology and Neurochemistry, Department of Neurology Medical University of Vienna  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia","family":"Wanschitz","sequence":"additional","affiliation":[{"name":"Department of Neurology Medical University of Innsbruck  Innsbruck Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alicia","family":"Alonso\u2010Jim\u00e9nez","sequence":"additional","affiliation":[{"name":"Department of Neurology, Antwerp University Hospital University of Antwerp  Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6192-6171","authenticated-orcid":false,"given":"Thais","family":"Armangu\u00e9","sequence":"additional","affiliation":[{"name":"Neuroimmunology program, IDIBAPS\u2010Hospital de Clinic; University of Barcelona. Pediatric Neuroimmunology Program, Neurology Department, Sant Joan de Deu Children's Hospital  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e1ja Elisabeth","family":"Baars","sequence":"additional","affiliation":[{"name":"Department of Neurology, Erasmus MC University Medical Center  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9282-8603","authenticated-orcid":false,"given":"\u00c1lvaro","family":"Carbayo","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Castek","sequence":"additional","affiliation":[{"name":"Department of Neurology Landeskrankenhaus Villach  Villach Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger","family":"Collet\u2010Vidiella","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"De Winter","sequence":"additional","affiliation":[{"name":"Department of Neurology, Antwerp University Hospital University of Antwerp  Antwerp Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria \u00c1ngeles","family":"del Real","sequence":"additional","affiliation":[{"name":"Department of Neurology General University Hospital of Ciudad Real  Ciudad Real Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilien","family":"Delmont","sequence":"additional","affiliation":[{"name":"Referral Centre for Neuromuscular Diseases and ALS Hospital La Timone  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Diamanti","sequence":"additional","affiliation":[{"name":"IRCCS Mondino Foundation  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro Emiliano","family":"Doneddu","sequence":"additional","affiliation":[{"name":"Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Rozzano, Department of Biomedical Sciences Humanitas University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu Liong","family":"Hiew","sequence":"additional","affiliation":[{"name":"Department of Neurology Sunway Medical Center  Bandar Sunway Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gallardo","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Neuromuscular Diseases Centro para la Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Raras (CIBERER)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaia","family":"Gonzalez","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Cruces  Barakaldo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susanne","family":"Grinzinger","sequence":"additional","affiliation":[{"name":"Department of Neurology Christian\u2010Doppler Klinik  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Horga","sequence":"additional","affiliation":[{"name":"Department of Neurology Neuromuscular Diseases Unit, University Hospital San Carlos  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Iglseder","sequence":"additional","affiliation":[{"name":"Department of Neurology Krankenhaus Barmherzige Br\u00fcder  Linz Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart C.","family":"Jacobs","sequence":"additional","affiliation":[{"name":"Department of Neurology, Erasmus MC University Medical Center  Rotterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaia","family":"Jauregui","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Cruces  Barakaldo Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joep","family":"Killestein","sequence":"additional","affiliation":[{"name":"Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisabeth Lindeck","family":"Pozza","sequence":"additional","affiliation":[{"name":"Department of Neurology Klinik Favoriten  Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Mart\u00ednez\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Department of Immunology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Nobile\u2010Orazio","sequence":"additional","affiliation":[{"name":"Neuromuscular and Neuroimmunology Unit, IRCCS Humanitas Research Hospital, Rozzano, Department of Medical Biotechnology and Translational Medicine Milan University  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolau","family":"Ortiz","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Sant Joan  Reus Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helena","family":"P\u00e9rez\u2010P\u00e9rez","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital of Canarias  Tenerife Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai\u2010Nicolas","family":"Poppert","sequence":"additional","affiliation":[{"name":"Department of Neurology Christian\u2010Doppler Klinik  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Ripellino","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurocenter of Southern Switzerland EOC, Faculty of Biomedical Sciences Universit\u00e0 della Svizzera Italiana  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Carlos","family":"Roche","sequence":"additional","affiliation":[{"name":"Department of Neurology University Hospital Miguel Servet  Zaragoza Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franscisco Javier","family":"Rodriguez de Rivera","sequence":"additional","affiliation":[{"name":"Department of Neurology, Instituto de Investigaci\u00f3n Sanitaria del Hospital Universitario La Paz\u2013IdiPAZ University Hospital La Paz, Universidad Aut\u00f3noma de Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Rostasy","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurology, Children's Hospital Datteln Witten\/Herdecke University  Datteln Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6190-1633","authenticated-orcid":false,"given":"Davide","family":"Sparasci","sequence":"additional","affiliation":[{"name":"Department of Neurology, Neurocenter of Southern Switzerland EOC, Faculty of Biomedical Sciences Universit\u00e0 della Svizzera Italiana  Lugano Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Tejada\u2010Illa","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charlotte C.E.","family":"Teunissen","sequence":"additional","affiliation":[{"name":"Neurochemistry Laboratory and Biobank, Department of Clinical Chemistry, Amsterdam UMC  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisa","family":"Vegezzi","sequence":"additional","affiliation":[{"name":"IRCCS Mondino Foundation  Pavia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom\u00e0s","family":"Xucl\u00e0\u2010Ferrarons","sequence":"additional","affiliation":[{"name":"Department of Neurology Hospital Sant Joan Desp\u00ed Mois\u00e8s Broggi  Sant Joan Desp\u00ed Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabian","family":"Zach","sequence":"additional","affiliation":[{"name":"Department of Neurology Kardinal Schwarzenberg Klinikum  Salzburg Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luuk","family":"Wieske","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Filip","family":"Eftimov","sequence":"additional","affiliation":[{"name":"Department of Neurology Amsterdam UMC location University of Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9971-0584","authenticated-orcid":false,"given":"Cinta","family":"Lleix\u00e0","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Neuromuscular Diseases Centro para la Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Raras (CIBERER)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Querol","sequence":"additional","affiliation":[{"name":"Neuromuscular Diseases Unit, Department of Neurology, Hospital de la Santa Creu i Sant Pau, Sant Pau Biomedical Research Institute (IIB Sant Pau) Universitat Aut\u00f2noma de Barcelona  Barcelona Spain"},{"name":"Neuromuscular Diseases Centro para la Investigaci\u00f3n Biom\u00e9dica en Red en Enfermedades Raras (CIBERER)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,11,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000001107"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2017-317192"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.23794"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aww189"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab014"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000002418"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001098"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awac418"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awx124"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2017.84"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/jns.12455"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0896-6273(01)00296-3"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20750"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awv054"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000771"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2014-309916"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0281156"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000149"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(06)70495-1"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2020.0781"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2020-323899"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00009-6"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(23)00210-7"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001040"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.759187"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.554"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000763"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000000602"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1212\/NXI.0000000000001163"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.16073"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2018.00997"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/mus.26392"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-020-10041-z"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13760-023-02463-z"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.939062"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00613"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa067752"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.528489"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2016-314895"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1021513"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105072"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.117.4.877"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1177\/13524585211010097"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/13524585221118676"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.27142","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,17]],"date-time":"2025-02-17T07:33:25Z","timestamp":1739777605000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.27142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,27]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1002\/ana.27142"],"URL":"https:\/\/doi.org\/10.1002\/ana.27142","archive":["Portico"],"relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.06.25.24309231","asserted-by":"object"}]},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,27]]},"assertion":[{"value":"2024-06-21","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}