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In six patients with unremitting TFNE, using high\u2010resolution post\u2010contrast magnetic resonance imaging and vessel wall imaging (VWI), we found various combinations of transient leptomeningeal, parenchymal and vessel wall enhancement; in 5 of 6 the enhancement included regions corresponding anatomically to symptoms. Three patients had resolution of TFNE and enhancement (2 with corticosteroid treatment, 1 without). Our observations suggest that inflammation might contribute to the pathophysiology of CAA\u2010related TFNE and cSAH, with potential wider relevance for the associated high risks of recurrent ICH in CAA more generally. 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