{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T21:01:53Z","timestamp":1698958913919},"reference-count":5,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":10110,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1977,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Although no therapeutic agent has proved to be of benefit in subacute sclerosing panencephalitis (SSPE), the use of Isoprinosine has been associated with clinical improvement in several preliminary reports. Two additional patients with SSPE are presented who had repeated serological and electroencephalographic studies during therapy with Isoprinosine. Their clinical courses are discussed in view of the laboratory findings and the natural history of the disease.<\/jats:p>","DOI":"10.1002\/ana.410010214","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T13:58:41Z","timestamp":1104587921000},"page":"183-184","source":"Crossref","is-referenced-by-count":16,"title":["The effect of isoprinosine in subacute sclerosing panencephalitis (SSPE)"],"prefix":"10.1002","volume":"1","author":[{"given":"L. J.","family":"Streletz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Cracco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"503","article-title":"Treatment of SSPE with Inoseplex: a preliminary report (abstract)","volume":"32","author":"Mattson RH","year":"1975","journal-title":"Arch Neurol"},{"key":"e_1_2_1_3_2","first-page":"364","article-title":"Isoprinosine therapy in subacute sclerosing panencephalitis (abstract)","volume":"26","author":"Huttenlocker PR","year":"1976","journal-title":"Neurology (Minneap)"},{"key":"e_1_2_1_4_2","first-page":"493","article-title":"SSPE: clinical staging, course and frequency (abstract)","volume":"32","author":"Jabbour JT","year":"1975","journal-title":"Arch Neurol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.35.2.180"},{"key":"e_1_2_1_6_2","first-page":"107","article-title":"Generalized sharp and slow wave and electrodecremental seizure patterns in subacute sclerosing panencephalitis","volume":"51","author":"Westmoreland BF","year":"1976","journal-title":"Mayo Clin Proc"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410010214","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410010214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T11:07:28Z","timestamp":1698923248000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410010214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,2]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1977,2]]}},"alternative-id":["10.1002\/ana.410010214"],"URL":"https:\/\/doi.org\/10.1002\/ana.410010214","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,2]]}}}