{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:28:19Z","timestamp":1788931699875,"version":"build-2803163510"},"reference-count":15,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":10051,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1977,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Alpha\u2010pattern coma denotes the association of a comatose state with an electroencephalogram consisting predominately of alpha\u2010frequency activity. Over the past three years we have studied 24 such cases: 14 following cardiopulmonary arrest, 6 following respiratory arrest, and 3 following brainstem infarction. Of the 9 patients who survived, only 1 had a significant neurological deficit. It was found that: (1) alpha\u2010pattern coma can result from a variety of neurological insults; (2) a significant proportion of patients survive, often with little or no deficit: (3) clinical evidence of intact brainstem function implies a favorable outcome; (4) the electroencephalogram was similar in survivors and nonsurvivors and did not differentiate diffuse cerebral dysfunction from focal brainstem disease; and (5) neuropathological studies demonstrated diffuse cortical as well as brainstem changes.<\/jats:p>","DOI":"10.1002\/ana.410010408","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:28:42Z","timestamp":1104539322000},"page":"371-377","source":"Crossref","is-referenced-by-count":49,"title":["Alpha\u2010pattern coma: 24 cases with 9 survivors"],"prefix":"10.1002","volume":"1","author":[{"given":"Alan B.","family":"Grindal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cary","family":"Suter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. Julio","family":"Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.18.4.357"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(64)90111-7"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(61)90111-0"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(53)90017-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.9.9.610"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(56)90095-5"},{"key":"e_1_2_1_8_2","first-page":"281","article-title":"Acute necrosis of the pons with long survival: electroclinical symptoms and absence of cerebral lesions","volume":"23","author":"Radermecker J","year":"1967","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.4.5730.265"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490530035001"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.6.582"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.7.655"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(75)90193-5"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(72)90032-6"},{"key":"e_1_2_1_15_2","volume-title":"Diagnosis of Stupor and Coma","author":"Plum F","year":"1966"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.11.1015"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410010408","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410010408","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T11:31:39Z","timestamp":1698924699000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410010408"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1977,4]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1977,4]]}},"alternative-id":["10.1002\/ana.410010408"],"URL":"https:\/\/doi.org\/10.1002\/ana.410010408","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1977,4]]}}}