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The microprobes identified a total of 11 elements in the VS in these 18 patients. Five elements\u2014lead, aluminum, sulfur, manganese, and barium\u2014were present only in VS associated with parkinsonism. Statistically, the association of lead was highly significant while that of aluminium and sulfur was only suggestive. Lead was present in 7 of the 10 patients with parkinsonism and aluminium and sufur in 4. The significance of the presence of sulfur is difficult to assess since its compounds are normally present in large quantities in the brain. These findings raise the question whether lead and aluminum may be associated in some way with the pathogenesis of certain forms of Parkinson disease.<\/jats:p>","DOI":"10.1002\/ana.410020308","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T22:50:11Z","timestamp":1104533411000},"page":"225-229","source":"Crossref","is-referenced-by-count":14,"title":["The relationship between parkinson syndrome and vascular siderosis: An electron microprobe study"],"prefix":"10.1002","volume":"2","author":[{"given":"Serge","family":"Duckett","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre","family":"Galle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Kradin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-194103000-00004"},{"key":"e_1_2_1_3_2","first-page":"77","article-title":"The vascular supply of the strio\u2010pallidum","volume":"21","author":"Alexander L","year":"1940","journal-title":"Res. 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