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In labor and delivery, lowest fetal heart rate in the second stage of labor, arrested progress of labor, and use of midforceps discriminated between the two groups. Neonatal characteristics of children who were later severely handicapped differed from controls, particularly with respect to difficulty in initiating and maintaining respiration, intracranial hemorrhage, neonatal seizures, low birth weight and small head circumference, lowest hemoglobin or hematocrit, and overall neurological status.<\/jats:p><jats:p>Multivariate analysis, including factors from all epochs, indicated that intracranial hemorrhage and neonatal seizures were the strongest independent discriminators between the neurologically impaired children and controls.<\/jats:p>","DOI":"10.1002\/ana.410020505","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T08:37:52Z","timestamp":1104482272000},"page":"371-377","source":"Crossref","is-referenced-by-count":78,"title":["Perinatal risk factors in children with serious motor and mental handicaps"],"prefix":"10.1002","volume":"2","author":[{"given":"Karin 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