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A first\u2010order rate constant, <jats:italic>k<\/jats:italic>, for metrizamide washout from the right lateral ventricle was determined with reference to mean ventricular metrizamide concentration on serial CAT scans; right ventricular volume, <jats:italic>V<\/jats:italic>, was estimated after metrizamide injection by multiplying the appropriate ventricular area on consecutive CAT slices by the nominal slice thickness. The rat of right lateral ventricular CSF formation, <jats:italic>I<\/jats:italic><jats:sub><jats:italic>f<\/jats:italic><\/jats:sub>, in our 3 patients was calculated as <jats:italic>k<\/jats:italic> \u00d7 <jats:italic>V<\/jats:italic> and ranged from 0.83 to 0.103 ml per minute.<\/jats:p>","DOI":"10.1002\/ana.410020610","type":"journal-article","created":{"date-parts":[[2004,12,31]],"date-time":"2004-12-31T22:53:00Z","timestamp":1104533580000},"page":"503-510","source":"Crossref","is-referenced-by-count":15,"title":["The rate of CSF formation in man: Preliminary observations on metrizamide washout as a measure of CSF bulk flow"],"prefix":"10.1002","volume":"2","author":[{"given":"David A.","family":"Rottenberg","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Howieson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D. 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