{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T08:23:16Z","timestamp":1788596596591,"version":"build-2803163510"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":8833,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1980,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We report 2 survivors of severe methanol poisoning who developed, apart from blindness, a Parkinson\u2010like extrapyramidal syndrome characterized by reduced initiative, poor voice volume, masked facies, mild tremor, rigidity, and bradykinesia. Both patients were mildly demented and 1 had hyperreflexia and bilateral Babinski responses.<\/jats:p><jats:p>Computed tomographic scans in both patients demonstrated bilateral symmetrical infarction of the frontocentral white matter and putamen. Electromyography in 1 patient showed extensive denervation, mainly involving the legs, but normal motor conduction velocities. <jats:sc>L<\/jats:sc>\u2010Dopa administered to the more severely affected patient had no effect on the parkinsonian features.<\/jats:p><jats:p>Autopsy revealed cystic resorption of the putamen and the frontocentral subcortical white matter in addition to widespread neuronal damage throughout the cerebrum, cerebellum, brainstem, and spinal cord.<\/jats:p>","DOI":"10.1002\/ana.410080206","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T12:25:29Z","timestamp":1104582329000},"page":"161-167","source":"Crossref","is-referenced-by-count":107,"title":["Methanol poisoning: A clinical and pathological study"],"prefix":"10.1002","volume":"8","author":[{"given":"Donald R.","family":"McLean","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harold","family":"Jacobs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce W.","family":"Mielke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.6142.929"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.11.1049"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005792-195312000-00002"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(77)80075-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(75)90174-X"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-195710000-00007"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/j.0954-6820.1965.tb00017.x","article-title":"Severe methanol intoxication","volume":"117","author":"Erlanson P","year":"1965","journal-title":"Acta Med Scand"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197805000-00009"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197301000-00008"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1976.00500010007002"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490330010002"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1974.00490330017003"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1971.00480360084011"},{"key":"e_1_2_1_15_2","first-page":"189","volume-title":"Selective Vulnerability of the Brain in Hypoxemia","author":"Lindenberg R","year":"1963"},{"key":"e_1_2_1_16_2","first-page":"2583","volume-title":"Pathology of the Nervous System","author":"Lindenberg R","year":"1971"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-2944(75)90171-4"},{"key":"e_1_2_1_18_2","first-page":"564","article-title":"Methanol poisoning: V. Role of formate metabolism in the monkey","volume":"201","author":"McMartin KE","year":"1977","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_1_19_2","first-page":"393","article-title":"Acute methyl alcohol poisoning: a report of 22 instances with post\u2010mortem methanol intoxication","volume":"117","author":"Menne FR","year":"1965","journal-title":"Acta Med Scand"},{"key":"e_1_2_1_20_2","volume-title":"Die Methylalcohol Vergiftung","author":"Orthner H","year":"1950"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00995451"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1970.tb49800.x"},{"key":"e_1_2_1_23_2","first-page":"346","article-title":"Schwere neurologische Ausfalle als Folge einer Methylalcohol Vergiftung","volume":"34","author":"Riegel H","year":"1966","journal-title":"Fortschr Neurol Psychiatr"},{"key":"e_1_2_1_24_2","first-page":"1665","volume-title":"Pathology of the Nervous System","author":"Scheidegger S","year":"1971"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.4.4.632"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410080206","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410080206","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T16:33:44Z","timestamp":1698942824000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410080206"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1980,8]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1980,8]]}},"alternative-id":["10.1002\/ana.410080206"],"URL":"https:\/\/doi.org\/10.1002\/ana.410080206","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1980,8]]}}}