{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T21:29:17Z","timestamp":1790976557371,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":8284,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1982,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>To study the relationship between fiber size and vulnerability to ischemia, we produced partial infarction of the proximal posterior tibial nerve of Wistar rats by injecting arachidonic acid into the ipsilateral femoral artery. In the resulting lesion degenerating fibers were concentrated in the center of the nerve. Distal to the infarct, surviving myelinated and unmyelinated fibers were evenly distributed throughout both fascicles. Smaller myelinated fibers (&lt;6\u03bcm in diameter) were more severely depleted than larger ones (&gt;6\u03bcm). Unmyelinated fibers were reduced in number in proportion to or to a greater extent than myelinated fibers. These findings demonstrate that large myelinated fibers are relatively less vulnerable to peripheral nerve ischemia than smaller fibers, and do not support the contention that unmyelinated fibers are inherently resistant to acute ischemia.<\/jats:p>","DOI":"10.1002\/ana.410110207","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T13:29:58Z","timestamp":1104586198000},"page":"147-154","source":"Crossref","is-referenced-by-count":79,"title":["Selective fiber vulnerability in acute ischemic neuropathy"],"prefix":"10.1002","volume":"11","author":[{"given":"Gareth J.","family":"Parry","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark J.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/93.3.555"},{"key":"e_1_2_1_3_2","volume-title":"Major Problems in Pathology","author":"Asbury AK","year":"1978"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410080207"},{"key":"e_1_2_1_5_2","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1152\/ajplegacy.1935.114.1.69","article-title":"Afferent function in the group of nerve fibers of slowest conduction velocity","volume":"114","author":"Clark D","year":"1935","journal-title":"Am J Physiol"},{"key":"e_1_2_1_6_2","first-page":"461","article-title":"Necrotizing angiopathic neuropathy","volume":"47","author":"Dyck PJ","year":"1972","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4886(67)90127-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114316"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.26.4.297"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/003693306200700602"},{"key":"e_1_2_1_11_2","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1152\/ajplegacy.1939.127.2.252","article-title":"Properties of mammalian B fibers","volume":"127","author":"Grundfest H","year":"1939","journal-title":"Am J Physiol"},{"key":"e_1_2_1_12_2","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1152\/ajplegacy.1929.89.1.58","article-title":"Effect of anoxemia, carbon dioxide and lactic acid on electrical phenomena of myelinated fibers of the peripheral nervous system","volume":"89","author":"Heinbecker P","year":"1929","journal-title":"Am J Physiol"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(79)90220-X"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(75)90009-X"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00684541"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197905173002006"},{"key":"e_1_2_1_17_2","first-page":"433","article-title":"Anatomical changes in peripheral nerves compressed by a pneumatic tourniquet","volume":"113","author":"Ochoa J","year":"1972","journal-title":"J Anat"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(81)90047-2"},{"key":"e_1_2_1_19_2","first-page":"129","article-title":"Diagnostic value of nerve biopsy in mononeuritis multiplex (abstract)","volume":"31","author":"Parry GJ","year":"1981","journal-title":"Neurology (NY)"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1968.00470350045004"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.183.4129.1085"},{"key":"e_1_2_1_22_2","first-page":"25","volume-title":"Nerve and Nerve Injuries","author":"Sunderland S","year":"1968"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410110207","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410110207","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,8]],"date-time":"2023-10-08T13:56:21Z","timestamp":1696773381000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410110207"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,2]]},"references-count":21,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1982,2]]}},"alternative-id":["10.1002\/ana.410110207"],"URL":"https:\/\/doi.org\/10.1002\/ana.410110207","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,2]]}}}