{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T20:58:13Z","timestamp":1784062693259,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":8195,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1982,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Intraneural injection of antisera from rabbits with high antigalactocerebroside antibody levels into rat sciatic nerve produced acute nerve conduction block. This was first apparent in some motor axons between 30 and 60 minutes after injection and progressed to completion within 2 to 4 hours. Concurrent morphological evidence of demyelination was present, but structural changes at the time of onset of block were mild and were restricted to the myelin and Schwann cell, particularly at the paranodal areas and Schmidt\u2010Lanterman clefts. It is suggested that paranodal lesions could account for the observed conduction block.<\/jats:p>","DOI":"10.1002\/ana.410110506","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T13:33:29Z","timestamp":1104586409000},"page":"469-477","source":"Crossref","is-referenced-by-count":89,"title":["Acute conduction block associated with experimental antiserum\u2010mediated demyelination of peripheral nerve"],"prefix":"10.1002","volume":"11","author":[{"given":"Austin J.","family":"Sumner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Saida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Saida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald H.","family":"Silberberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arthur K.","family":"Asbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/263786a0"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090712"},{"key":"e_1_2_1_4_2","first-page":"363","article-title":"Passive transfer of demyelinating activity in Guillain\u2010Barr\u00e9 polyneuropathy","volume":"30","author":"Feasby TE","year":"1980","journal-title":"Neurology (NY)"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(76)90146-0"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00707103"},{"key":"e_1_2_1_7_2","first-page":"204","article-title":"Experimental diphtheritic neuropathy in the rat","volume":"48","author":"Jacobs JM","year":"1967","journal-title":"Br J Exp Pathol"},{"key":"e_1_2_1_8_2","first-page":"295","article-title":"Species differences in internode formation following two types of peripheral nerve injury","volume":"105","author":"Jacobs JM","year":"1969","journal-title":"J Anat"},{"key":"e_1_2_1_9_2","first-page":"29","article-title":"Nerve function studies in experimental polyneuritis","volume":"22","author":"Kaeser HE","year":"1962","journal-title":"Electroencephalogr Clin Neurophysiol (suppl)"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1972.sp010036"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/199575a0"},{"key":"e_1_2_1_12_2","first-page":"371","article-title":"Electrodiagnostic distinction between chronic acquired and familial demyelinative neuropathies","volume":"30","author":"Lewis RA","year":"1980","journal-title":"Neurology (NY)"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/86.3.501"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1970.sp009076"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1972.sp010035"},{"key":"e_1_2_1_16_2","first-page":"371","article-title":"Development of conduction block in single rat spinal root fibers locally exposed to antigalactocerebroside serum","volume":"30","author":"Rasminsky M","year":"1980","journal-title":"Neurology (NY)"},{"key":"e_1_2_1_17_2","first-page":"65","article-title":"Conduction block caused by antigalactocerebroside serum is due to paranodal demyelination","volume":"31","author":"Rasminsky M","year":"1981","journal-title":"Neurology"},{"key":"e_1_2_1_18_2","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1212\/WNL.31.4_Part_2.413","article-title":"Axonal lesions in acute experimental demyelination: a sequential teased nerve fiber study","volume":"31","author":"Said G","year":"1981","journal-title":"Neurology (NY)"},{"key":"e_1_2_1_19_2","first-page":"99","article-title":"In vivo demyelination induced by intraneural injuection of anti\u2010galactocerebroside serum: a morphologic study","volume":"95","author":"Saida K","year":"1979","journal-title":"Am J Pathol"},{"key":"e_1_2_1_20_2","first-page":"449","article-title":"Antiserum\u2010mediated demyelination in vivo: a sequential study using intraneural injection of experimental allergic neuritis serum","volume":"39","author":"Saida K","year":"1978","journal-title":"Lab Invest"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410080103"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005072-197909000-00005"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.451555"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410110112"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691786"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/272639a0"},{"key":"e_1_2_1_27_2","first-page":"581","article-title":"Acute conduction block produced by intraneural injection of EAE serum: a correlative electrophysiological and morphological study","volume":"29","author":"Sumner AJ","year":"1979","journal-title":"Neurology (NY)"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410110506","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410110506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,2]],"date-time":"2023-11-02T07:09:05Z","timestamp":1698908945000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410110506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,5]]},"references-count":26,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1982,5]]}},"alternative-id":["10.1002\/ana.410110506"],"URL":"https:\/\/doi.org\/10.1002\/ana.410110506","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1982,5]]}}}