{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T05:28:14Z","timestamp":1788931694844,"version":"build-2803163510"},"reference-count":18,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":7646,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1983,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 13\u2010year\u2010old boy with imipramine overdose developed seizures, respiratory arrest, and coma. Abnormalities of oculovestibular reflexes, electroencephalograms, and brainstem auditory evoked potentials were monitored in relation to measurements of drug levels. An alpha\u2010coma electroencephalographic pattern evolved into one evidencing spindle coma and eventually into a normal pattern. Prolonged brainstem auditory evoked potentials also normalized as coma and oculocephalic reflex abnormalities resolved. In spite of the history that suggested hypoxic damage, the absence of reflex eye movements in a comatose patient and the presence of alphaand spindle\u2010coma electroencephalographic patterns, even with prolonged brainstem auditory evoked potentials, are not reliable prognostic indicators in tricyclic drug overdose.<\/jats:p>","DOI":"10.1002\/ana.410140516","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:02:06Z","timestamp":1104598926000},"page":"587-590","source":"Crossref","is-referenced-by-count":28,"title":["External ophthalmoplegia, alpha and spindle coma in imipramine overdose: Case report and review of the literature"],"prefix":"10.1002","volume":"14","author":[{"given":"Stefan\u2010M.","family":"Pulst","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. T.","family":"Lombroso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"269","article-title":"Su di un particolare quadro EEG del coma acuto traumatico caratterizzato dalla presenza di spindles","volume":"40","author":"Bricolo A","year":"1980","journal-title":"Riv Neurol"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.4_Part_2.393"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(63)90096-8"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.25.7.655"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410010408"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.1.83"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090617"},{"key":"e_1_2_1_9_2","first-page":"168","article-title":"Interrelationships between cortex and subcortical structures: clinical electroencephalographic studies","volume":"4","author":"Jasper HH","year":"1953","journal-title":"Electroencephalogr Clin Neurophysiol (Suppl)"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.10.1359"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090620"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(53)90017-0"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.27.7.695"},{"key":"e_1_2_1_14_2","first-page":"512","article-title":"\u00c9tude \u00e9lectro\u00e9ncephalographique des traumatisms craniens recents dans un service de r\u00e9animation","volume":"117","author":"Naquet R","year":"1967","journal-title":"Rev Neurol (Paris)"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.43.1.63"},{"key":"e_1_2_1_16_2","volume-title":"The Diagnosis of Stupor and Coma","author":"Plum F","year":"1966"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-91-5-793_3"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1975.00490530035001"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.6.582"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410140516","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410140516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,19]],"date-time":"2023-10-19T01:57:19Z","timestamp":1697680639000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410140516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1983,11]]},"references-count":18,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1983,11]]}},"alternative-id":["10.1002\/ana.410140516"],"URL":"https:\/\/doi.org\/10.1002\/ana.410140516","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1983,11]]}}}