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The stellate neurons of tubers had beaded or varicose dendrites with few dendritic spines. The findings suggest that neurons within tubers are an aberrant primitive cell type that fails to express the pyramidal cell shape and dendritic morphology that is characteristic of normal human neocortex. Cortex intervening between tubers had basically normal dendritic morphology. However, quantitative study showed a decrease in the length of dendritic branches of pyramidal neurons, as also observed in several other conditions manifested by mental retardation.<\/jats:p>","DOI":"10.1002\/ana.410160511","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:16:46Z","timestamp":1104599806000},"page":"595-602","source":"Crossref","is-referenced-by-count":65,"title":["Fine structure of cortical tubers in tuberous sclerosis: A Golgi study"],"prefix":"10.1002","volume":"16","author":[{"given":"Peter R.","family":"Huttenlocher","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter T.","family":"Heydemann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,16]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00688497"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/55.3.311"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(80)91035-5"},{"key":"e_1_2_1_5_2","volume-title":"Tuberous Sclerosis","author":"Gomez MR","year":"1979"},{"key":"e_1_2_1_6_2","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1007\/BF00692311","article-title":"Neurofibrillary changes, granulovacuolar bodies and argentophilic globules observed in tuberous sclerosis","volume":"11","author":"Hirano A","year":"1968","journal-title":"Acta Neuropathol (Berl)"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.3.203"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-139050-1.50013-6"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901760203"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00522529"},{"key":"e_1_2_1_11_2","volume-title":"The Cell Surface in Development","author":"Moscona AA","year":"1974"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00687869"},{"key":"e_1_2_1_13_2","volume-title":"The Retina","author":"Polyak SL","year":"1941"},{"key":"e_1_2_1_14_2","first-page":"1","article-title":"Ein Herz von einem Neugeborenen welches mehrere teils nach aussen teils nach den Hoehlen Prominirende Tumoren (Myomen) trug","volume":"20","author":"Von Recklinghausen F","year":"1862","journal-title":"Monatsschr Geburtsk"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00691754"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237491"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1038\/171387a0"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00688011"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901920206"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.20.2.139"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410090211"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410160511","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410160511","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T17:51:36Z","timestamp":1697824296000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410160511"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1984,11]]},"references-count":20,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1984,11]]}},"alternative-id":["10.1002\/ana.410160511"],"URL":"https:\/\/doi.org\/10.1002\/ana.410160511","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1984,11]]}}}