{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,10,21]],"date-time":"2023-10-21T16:40:18Z","timestamp":1697906418360},"reference-count":10,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2004,10,7]],"date-time":"2004-10-07T00:00:00Z","timestamp":1097107200000},"content-version":"vor","delay-in-days":7188,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1985,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Mice inoculated intracerebrally before the age of 5 days with homogenates of autopsied brain tissue from patients with Creutzfeldt\u2010Jakob (C\u2010J), Alzheimer's, or Pick's diseases showed highly significant decreases in life span when compared with sham\u2010inoculated control mice. With C\u2010J disease there was strong indication of horizontal transmission of the agent to unionculated mice caged with the inoculated mice. While the results with C\u2010J disease were not unexpected in view of the known infectious etiology of the disease, the results obtained with Alzheimer's and Pick's diseases suggest that previously undetermined infectious or toxic agents may be associated with these who diesease, which currently have unresolved etiologies. Mice inoculated with autopsied brain tissue from patients with multiple scelrosis or subacute sclerosing panencephalitis had life spans similar to those of the control mice.<\/jats:p>","DOI":"10.1002\/ana.410170219","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:19:42Z","timestamp":1104599982000},"page":"206-209","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of survival times of mice inoculated with brain tissue from various neurological diseases"],"prefix":"10.1002","volume":"17","author":[{"given":"Leighton W.","family":"Greenham","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Peacock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,7]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"144","volume-title":"Slow Viruses","author":"Adams DH","year":"1976"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(75)90102-6"},{"key":"e_1_2_1_4_2","first-page":"963","article-title":"Experimental transmission of Creutzfeldt\u2010Jakob disease to guinea pigs","volume":"31","author":"Chino F","year":"1981","journal-title":"Acta Pathol Jpn"},{"key":"e_1_2_1_5_2","first-page":"559","volume-title":"Senile Dementia and Related Disorders. Aging","author":"Gibbs CJ","year":"1978"},{"key":"e_1_2_1_6_2","first-page":"87","volume-title":"Slow Transmissible Diseases of the Nervous System","author":"Gibbs CJ","year":"1979"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01250219"},{"key":"e_1_2_1_8_2","series-title":"Progress in Neuroepidemiology series","first-page":"170","volume-title":"Clinical Neuroepidemiology","author":"Kurtzke JF","year":"1980"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/271778a0"},{"key":"e_1_2_1_10_2","first-page":"943","article-title":"Experimental transmission of Creutzfeldt\u2010Jakob disease","volume":"31","author":"Tateishi J","year":"1981","journal-title":"Acta Pathol Jpn"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1982.tb26848.x"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410170219","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410170219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T19:08:57Z","timestamp":1697828937000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410170219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1985,2]]}},"alternative-id":["10.1002\/ana.410170219"],"URL":"https:\/\/doi.org\/10.1002\/ana.410170219","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1985,2]]}}}