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Computed tomographic examinations showed variable degrees of cortical atrophy with ventricular dilatation and calcification. Electrophysiological abnormalities were demonstrated. Two children had documented central nervous system infections. Neurological deterioration resulted in dementia in 3 children. Cognitive impairment and developmental delays were evident in the other 3. Postmortem examination of the 3 children who died showed subacute cytomegalovirus encephalitis in 1; nonspecific hemispheric white matter changes, calcific vasopathy of the basal ganglia, and striking bilateral corticospinal tract degeneration in the second; and extensive calcific vasopathy of the basal ganglia and frontal centrum semiovale, and bilateral attenuation of the frontopontine and corticospinal tracts in the third.<\/jats:p>","DOI":"10.1002\/ana.410180509","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:26:31Z","timestamp":1104600391000},"page":"560-566","source":"Crossref","is-referenced-by-count":213,"title":["Neurological complications in infants and children with acquired immune deficiency syndrome"],"prefix":"10.1002","volume":"18","author":[{"given":"Anita Lesgold","family":"Belman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica 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