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In 5 patients the blink reflex consisted of three components, and in 1 patient it consisted of four components, with two components being normal. The second component of their blink reflex did not habituate. Other abnormalities included long\u2010latency responses in the extremities in 2 patients, release of H\u2010reflexes from flexor hallucis brevis muscle in 2 patients, and an H<jats:sub>max<\/jats:sub>\/M<jats:sub>max<\/jats:sub> ratio of 98% in 2 patients. One patient's median nerve somatosensory\u2010evoked response had a markedly enlarged P<jats:sub>22<\/jats:sub> wave. These electrophysiological abnormalities suggest a disorder of the central nervous system producing increased excitability of segmental reflexes. To produce increased excitability of both brainstem and spinal cord reflexes, the disorder must be operative at the pontine level or rostral to it. Since long\u2010latency components of blink reflexes occurred in all our patients, this may be a helpful diagnostic test when PLMS is suspected.<\/jats:p>","DOI":"10.1002\/ana.410190210","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:27:52Z","timestamp":1104600472000},"page":"168-173","source":"Crossref","is-referenced-by-count":56,"title":["Periodic leg movements of sleep (nocturnal myoclonus): An electrophysiological study"],"prefix":"10.1002","volume":"19","author":[{"given":"Lawrence R.","family":"Wechsler","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John W.","family":"Stakes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhaghwan T.","family":"Shahani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neil A.","family":"Busis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"204","volume-title":"Evoked potentials in clinical medicine","author":"Chiappa KH","year":"1983"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410080413"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(77)90155-9"},{"key":"e_1_2_1_5_2","first-page":"508","volume-title":"New Developments in Electromyography and Clin\u00efcal Neurophysiology","author":"Delwaide PJ","year":"1973"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-409-95144-8.50009-4"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1956.sp005452"},{"key":"e_1_2_1_8_2","first-page":"616","article-title":"An electrophysiological study of myoclonus (abstract)","volume":"43","author":"Egloff\u2010Baer S","year":"1977","journal-title":"Electroencephalogr Clin Neurophysiol"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.28.12.1265"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.29.1.45"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00237390"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1969.sp008968"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410150304"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1981.sp013617"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0013-4694(64)90229-9"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.31.5.581"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1970.00480200062006"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.24.2.168"},{"key":"e_1_2_1_19_2","first-page":"773","volume-title":"Motor Control Mechanisms in Health and Disease","author":"Kimura J","year":"1983"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.35.2.228"},{"key":"e_1_2_1_21_2","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1152\/ajplegacy.1923.67.1.141","article-title":"Studies on the physiology of sleep. 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