{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:23:26Z","timestamp":1791095006073,"version":"4.1.0"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":6186,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1987,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>We used magnetic resonance imaging to determine the volume of the mamillary bodies in 9 patients with chronic Wernicke's encephalopathy, 7 patients with presumed Alzheimer's disease, and 37 control patients. The mean mamillary body volume (\u00b1 standard error) was 21.3 \u00b1 5.8 mm<jats:sup>3<\/jats:sup> in Wernicke patients, 40.1 \u00b1 3.7 mm<jats:sup>3<\/jats:sup> in Alzheimer patients, and 51.7 \u00b1 2.5 mm<jats:sup>3<\/jats:sup> in control patients. Seven of nine (78%) patients with chronic Wernicke's encephalopathy had smaller mamillary bodies than 36 of 37 control patients and 7 of 7 Alzheimer patients. The decrease in mamillary body volume was related neither to patient age nor to degree of ventricular enlargement, and most likely reflects the mamillary body atrophy that is grossly apparent at autopsy in up to 81% of Wernicke patients. This technique provides a means of identifying the most specific macroscopic lesion of chronic Wernicke's encephalopathy.<\/jats:p>","DOI":"10.1002\/ana.410220506","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T17:51:10Z","timestamp":1104601870000},"page":"595-600","source":"Crossref","is-referenced-by-count":99,"title":["Mamillary body atrophy in Wernicke's encephalopathy: Antemortem identification using magnetic resonance imaging"],"prefix":"10.1002","volume":"22","author":[{"given":"Michael E.","family":"Charness","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"DeLaPaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","unstructured":"BydderGMNiendorfHPYoungIR:Fast T2 dependent field echo imaging in neurological disease. 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