{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:32:30Z","timestamp":1774467150055,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":4970,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>A 9\u2010year\u2010old, blind boy with severe mental retardation with a chronic sleep\/wake disturbance had a circadian rhythm of 24.75 hours and an internal desynchronization of the endogenous rhythms. Treatment with oral melatonin given at 6<jats:sc>PM<\/jats:sc> induced a regular sleep\/wake pattern. Melatonin, in this patient, convincingly entrained the endogenous rhythm to the appropriate chronological 24\u2010hour day.<\/jats:p>","DOI":"10.1002\/ana.410290318","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T11:57:02Z","timestamp":1104580622000},"page":"336-339","source":"Crossref","is-referenced-by-count":108,"title":["Correction of non\u201324\u2010hour sleep\/wake cycle by melatonin in a blind retarded boy"],"prefix":"10.1002","volume":"29","author":[{"given":"Lars","family":"Palm","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00f6sta","family":"Blennow","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lennart","family":"Wetterberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"277","article-title":"Circadian rhythms of body temperature and sleep latency in blind subjects with sleepiwake complaints","volume":"9","author":"Stavosky JM","year":"1980","journal-title":"Sleep Res"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.910139"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/10.2.101"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198308253090806"},{"key":"e_1_2_1_6_2","first-page":"3","article-title":"Melatonin: a link between the environment and bchavior","volume":"5","author":"Frazer A","year":"1987","journal-title":"Integr Psychiatry"},{"key":"e_1_2_1_7_2","first-page":"396","article-title":"Melatonin administration phase advances endogenous rhythms in humans","volume":"17","author":"Sack RL","year":"1988","journal-title":"Sleep Res"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/00140138708966031"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(88)91586-3"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(78)90130-4"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/cne.901460102"},{"key":"e_1_2_1_12_2","first-page":"109","article-title":"Melatonin administration and nocturnal sleep in insomniacs","volume":"16","author":"Mendelson WB","year":"1987","journal-title":"Sleep Res"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1159\/000181088"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1159\/000123997"},{"key":"e_1_2_1_15_2","first-page":"1","volume-title":"Melatonin: clinical perspectives","author":"Reiter RJ","year":"1988"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410290318","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410290318","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T21:58:18Z","timestamp":1695851898000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410290318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1002\/ana.410290318"],"URL":"https:\/\/doi.org\/10.1002\/ana.410290318","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}