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Rat pups carried bipolar electrodes implanted in subcortical limbic structures, as well as cortical electrodes and intracerebroventricular cannulae. The administration of corticotropin\u2010releasing hormone produced age\u2010specific seizures within minutes, which correlated with rhythmic amygdala discharges. Paroxysmal hippocampal and cortical discharges developed subsequently in some rats. Corticotropin\u2010releasing hormone\u2013induced electrographic and behavioral seizures originate in the amygdala.<\/jats:p>","DOI":"10.1002\/ana.410310505","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T12:11:34Z","timestamp":1104581494000},"page":"488-494","source":"Crossref","is-referenced-by-count":98,"title":["Corticotropin\u2010releasing hormone\u2013induced seizures in infant rats originate in the amygdala"],"prefix":"10.1002","volume":"31","author":[{"given":"Tallie Z.","family":"Baram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"O. 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