{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T11:46:16Z","timestamp":1792842376877,"version":"4.5.0"},"reference-count":31,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":4208,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1993,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>In northern China, annual epidemics of acute\u2010onset flaccid paralysis diagnosed clinically as Guillain\u2010Barr\u00e9 syndrome have been recognized for at least 20 years. On the basis of an historical analysis of more than 3,200 patients, distinctvie features include most cases occurring during the summer months among children and young adults, most of whom reside in rural areas. Of 90 patients with acute flaccid paralysis, 88 had a distinctive pattern that shares clinical and cerebrospinal fluid findings with demyelinating Guillain\u2010Barr\u00e9 syndrome, but that differs from Guillain\u2010Barr\u00e9 syndrome physiologically and pathologically. The clinical course is marked by rapidly progressive ascending tetraparesis, often with respiratory failure, but without fever, systemic illness, or sensory involvement. Cerebrospinal fluid is acellular, and elevations of protein content occur in the second or third week of illness. Electrodiagnostic studies show normal motor distal latencies and limb conduction velocities, but reduced compound muscle action potential amplitudes. Sensory nerve action potentials and, when elicitable, F waves are within the range of normal. Recovery is usually good. Autopsy studies have shown Wallerian\u2010like degeneration of motor fibers. These studies establish that this is a distinctive syndrome, distinguishable from poliomyelitis and demyelinating Guillain\u2010Barr\u00e9 syndrome.<\/jats:p>","DOI":"10.1002\/ana.410330402","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T14:37:07Z","timestamp":1104590227000},"page":"333-342","source":"Crossref","is-referenced-by-count":470,"title":["Acute motor axonal neuropathy: A frequent cause of acute flaccid paralysis in China"],"prefix":"10.1002","volume":"33","author":[{"given":"G. M.","family":"McKhann","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. R.","family":"Cornblath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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