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In the anterior hippocampus ipsilateral to the electrical focus, <jats:sup>123<\/jats:sup>I\u2010iododexetimide binding was decreased by 40 \u00b1 9% (mean 7plusmn; SD, <jats:italic>p<\/jats:italic> &lt;0.01) compared with the contralateral hippocampus; <jats:sup>123<\/jats:sup>I\u2010iododexetimide binding in other temporal lobe regions was symmetrical. The data indicate a regionally specific change of muscarinic acetylcholine receptor in anterior hippocampus in complex partial seizures of temporal lobe origin.<\/jats:p>","DOI":"10.1002\/ana.410340221","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:24:54Z","timestamp":1104539094000},"page":"235-238","source":"Crossref","is-referenced-by-count":35,"title":["Decreased hippocampal muscarinic cholinergic receptor binding measured by <sup>123<\/sup>I\u2010iododexetimide and single\u2010photon emission computed tomography in epilepsy"],"prefix":"10.1002","volume":"34","author":[{"given":"Hans W.","family":"M\u00fcller\u2010G\u00e4rtner","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen S.","family":"Mayberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Fisher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ronald P.","family":"Lesser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan A.","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hayden T.","family":"Ravert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert F.","family":"Dannals","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Henry N.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sumio","family":"Uematsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. 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