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To better understand the pathogenesis of this symptom in a community\u2010dwelling population, we studied 26 patients &gt;75 years old who complained of disequilibrium in whom no cause was evident after clinical evaluation. Each patient and each of 26 age\u2010matched controls underwent a comprehensive evaluation that included a history and examination, a questionnaire, functional scales, a gait and balance scale, mini\u2010mental state testing, audiometry, visual acuity, visual tracking, rotational vestibular testing, and quantitative posturography. Although none had Romberg's sign, patients tended to sway more and do poorer on semiquantitative gait and balance testing than did controls. Patients showed few differences from controls for most other measurements. However, 7 patients, designated Group V, had profoundly reduced vestibular function. In the remaining 19 patients (Group D), the average vestibular function was still significantly lower than controls. Sway velocity measured with posturography was increased in the patients compared with controls, particularly in Group V patients. Measures of vestibular function correlated with increased sway velocity both in Group D alone and among all study participants. Quantitative measurement of vestibular function should be considered in older people complaining of disequilibrium, particularly if the cause is not apparent after the initial evaluation.<\/jats:p>","DOI":"10.1002\/ana.410340512","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:27:57Z","timestamp":1104539277000},"page":"694-702","source":"Crossref","is-referenced-by-count":70,"title":["Disequilibrium of unknown cause in older people"],"prefix":"10.1002","volume":"34","author":[{"given":"Terry D.","family":"Fife","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Baloh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"925","article-title":"The prevalence of dysequilibrium and related disorders in older persons","volume":"68","author":"Weindruch R","year":"1989","journal-title":"Ear Nose Throat J"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(86)90717-5"},{"key":"e_1_2_1_4_2","first-page":"261","article-title":"Balance function in elderly people who have and have not fallen","volume":"69","author":"Ring C","year":"1988","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/46.4.M114"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198812293192604"},{"key":"e_1_2_1_7_2","volume-title":"Development of posture and gait across the life span","author":"Horak FB","year":"1989"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348947208100203"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016487309121518"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.3109\/00016487509124657"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/00034894790880S201"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-94-011-7283-7_4"},{"key":"e_1_2_1_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/geronj\/46.3.M69"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1002\/jor.1100010307"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00231755"},{"key":"e_1_2_1_16_2","first-page":"619","article-title":"Visual perception of verticality and horizontality among elderly fallers","volume":"62","author":"Tobis JS","year":"1981","journal-title":"Arch Phys Med Rehabil"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1988.tb04365.x"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1177\/155005949202300211"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.11.2069"},{"key":"e_1_2_1_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2990.1975.tb00652.x"},{"key":"e_1_2_1_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(86)90176-0"},{"key":"e_1_2_1_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1992.00530280106030"},{"key":"e_1_2_1_23_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410130326"},{"key":"e_1_2_1_24_2","doi-asserted-by":"publisher","DOI":"10.1002\/mds.870020101"},{"key":"e_1_2_1_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1989.00520480034016"},{"key":"e_1_2_1_26_2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.22.4.323"},{"key":"e_1_2_1_27_2","first-page":"248","article-title":"Vertigo and imbalance in the elderly","volume":"15","author":"McClure JA","year":"1986","journal-title":"J Otolaryngol"},{"key":"e_1_2_1_28_2","doi-asserted-by":"publisher","DOI":"10.1136\/jech.35.3.200"},{"key":"e_1_2_1_29_2","first-page":"413P","article-title":"The effect of ageing on measured responses to single doses of temazepam","volume":"11","author":"Swift CG","year":"1981","journal-title":"Br J Clin Pharmacol"},{"key":"e_1_2_1_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0197-4580(89)90010-9"},{"key":"e_1_2_1_31_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100100520"},{"key":"e_1_2_1_32_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.1989.tb06916.x"},{"key":"e_1_2_1_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3956(75)90026-6"},{"key":"e_1_2_1_34_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1963.03060120024016"},{"key":"e_1_2_1_35_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2007.01590.x"},{"key":"e_1_2_1_36_2","first-page":"563","article-title":"On\u2010line analysis of eye movements using a digital computer","volume":"51","author":"Baloh RW","year":"1980","journal-title":"Aviat Space Environ Med"},{"key":"e_1_2_1_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0196-0709(82)80002-1"},{"key":"e_1_2_1_38_2","doi-asserted-by":"crossref","unstructured":"GrabinerMD LundinTM FeuerbachJW . 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