{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T02:20:21Z","timestamp":1792376421252,"version":"4.4.0"},"reference-count":18,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":3599,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1994,12]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>During 1990 to 1991, through a national surveillance program for poliomyelitis, the Paraguayan Ministry of Health received reports of 50 children with incident acute flaccid paralysis (&lt; 15 years old). On the basis of established criteria, 37 were diagnosed with Guillian\u2010Barr\u00e9 syndrome. The average annual incidence rate for 1990 to 1991 was 1.1\/100,000 children. The clinical course was more benign than reported in other pediatric series. There were low rates of hospitalization (57%), respiratory compromise (8%), and intubation (5%). The overall severity, however, was similar to that described in previous reports, with a 3% case\u2010fatality rate and an 81% total recovery rate at 12 months. Seventy\u2010six percent of patients had symptom onset during January to April, the warmest months of the year. Thirty percent of patients had definite or possible exposure to organophosphate pesticides, and the peak use coincides with the peak incidence of Guillian\u2010Barr\u00e9 syndrome There was no correlation between occurrence of Guillian\u2010Barr\u00e9 syndrome and prior immunization.<\/jats:p>","DOI":"10.1002\/ana.410360609","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T16:10:57Z","timestamp":1104595857000},"page":"859-863","source":"Crossref","is-referenced-by-count":42,"title":["Childhood Guillain\u2010Barr\u00e9 syndrome in Paraguay, 1990 to 1991"],"prefix":"10.1002","volume":"36","author":[{"given":"David E.","family":"Hart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura A.","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana A.","family":"Ros\u00e0rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Humberto","family":"Recalde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo C.","family":"Rom\u00e0","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00314485"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1987.tb07901.x"},{"key":"e_1_2_1_4_2","first-page":"565","article-title":"Criteria for diagnosis of Guillian\u2010Barr\u00e9 syndrome (NINCDS Ad\u2010hoc Committee)","volume":"3","author":"Asbury K","year":"1978","journal-title":"Ann Neurol"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410270707"},{"key":"e_1_2_1_6_2","first-page":"94","volume-title":"Anuario estadistico del Paraguay: 1990","author":"Rodriguez K","year":"1991"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880150415"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)90609-0"},{"key":"e_1_2_1_9_2","first-page":"427","article-title":"The Landry\u2010Guillain\u2010Barr\u00e9\u2010Strohl syndrome or polyradiculoneuropathy: historical review, report on 97 patients, and present concepts","volume":"39","author":"Wiederholt K","year":"1964","journal-title":"Mayo Clin Proc"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/77.3.1297"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1987.tb120153.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1445-5994.1989.tb00335.x"},{"key":"e_1_2_1_13_2","first-page":"260","article-title":"Electrophysiology of acute paralytic disease of children and young adults in northern China","volume":"30","author":"Cornblath K","year":"1991","journal-title":"Ann Neurol"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90606-P"},{"key":"e_1_2_1_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.1991.tb14931.x"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.52.7.853"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.62.7.733"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1136\/adc.66.6.706"},{"key":"e_1_2_1_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.1988.tb03632.x"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410360609","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410360609","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,24]],"date-time":"2023-10-24T06:46:56Z","timestamp":1698130016000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410360609"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,12]]},"references-count":18,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1994,12]]}},"alternative-id":["10.1002\/ana.410360609"],"URL":"https:\/\/doi.org\/10.1002\/ana.410360609","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1994,12]]}}}