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Two types of self\u2010paced voluntary arm movements were examined: repetitive forward movement of a joystick, and random\u2010choice movements of the same joystick in which subjects had to choose freely the direction in which they were to move the stick (forward, backward, left, or right). In normal subjects, the movement\u2010related cortical potential was larger prior to random\u2010choice movements, whereas in the patients, the amplitude was the same in both tasks. The implication is that processes involved in self\u2010selection of movement are abnormal in Parkinson's disease. This may contribute to the difficulty that patients have in initiating voluntary movement in the absence of any external cues.<\/jats:p>","DOI":"10.1002\/ana.410370613","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T13:58:48Z","timestamp":1104587928000},"page":"791-799","source":"Crossref","is-referenced-by-count":46,"title":["Movement\u2010related cortical potentials preceding repetitive and random\u2010choice hand movements in parkinson's disease"],"prefix":"10.1002","volume":"37","author":[{"given":"T.","family":"Touge","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. J.","family":"Werhahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Rothwell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. 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