{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T15:01:32Z","timestamp":1790521292175,"version":"4.1.0"},"reference-count":13,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2004,10,8]],"date-time":"2004-10-08T00:00:00Z","timestamp":1097193600000},"content-version":"vor","delay-in-days":2472,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Annals of Neurology"],"published-print":{"date-parts":[[1998,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Narcolepsy was diagnosed in 51 children (29 boys). The age range was 2.1 to 11.8 years (mean, 7.9 \u00b1 3.1 years). A mean of three referrals was made before narcolepsy was considered. In 10 children, cataplexy was the presenting symptom. Thirty\u2010eight children acknowledged sleep paralysis and 30 acknowledged hypnagogic hallucinations. All children had sleep studies; 31 exhibited rapid eye movement at sleep onset. The mean sleep latency was 1.5 minutes \u00b1 39 seconds on the Multiple Sleep Latency Test. All children had at least two sleep\u2010onset rapid eye movement sleep episodes in this test. Forty\u2010six children were HLA class II\u2013positive for DQw6, and 45 were also positive for DRw15. Thirty (65%) families refused referrals to support and counseling groups. Teachers often refused to acknowledge a medical problem. During follow\u2010up, all children presented at least once with depressive symptoms in reaction to their syndrome. Narcolepsy should be considered when evaluating children with behavioral and depressive symptoms.<\/jats:p>","DOI":"10.1002\/ana.410430125","type":"journal-article","created":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T15:10:19Z","timestamp":1104592219000},"page":"135-142","source":"Crossref","is-referenced-by-count":125,"title":["Narcolepsy in prepubertal children"],"prefix":"10.1002","volume":"43","author":[{"given":"Christian","family":"Guilleminault","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Pelayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,10,8]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"171","volume-title":"Narcolepsy","author":"Navelet Y","year":"1996"},{"key":"e_1_2_1_3_2","volume-title":"Sleeping and waking disorders: indications and techniques","author":"Miles L","year":"1982"},{"key":"e_1_2_1_4_2","volume-title":"A manual of standardized terminologyS, techniques and scoring systems for sleep stages of human subjects","author":"Rechtschaffen A","year":"1968"},{"key":"e_1_2_1_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/9.4.519"},{"key":"e_1_2_1_6_2","first-page":"203","article-title":"Positive HLA DR2 findings as a prerequisite for the development of narcolepsy","volume":"39","author":"Honda Y","year":"1985","journal-title":"Folia Psychiatr Neurol Jpn"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)91977-6"},{"key":"e_1_2_1_8_2","doi-asserted-by":"crossref","first-page":"S60","DOI":"10.1093\/sleep\/17.suppl_8.S60","article-title":"DQB1\u20100602 and DQA1\u20100102 (DQ1) are better markers than DR2 for narcolepsy in Caucasian and black Americans","volume":"17","author":"Mignot E","year":"1994","journal-title":"Sleep"},{"key":"e_1_2_1_9_2","volume-title":"Growth at adolescence","author":"Tanner JM","year":"1962"},{"key":"e_1_2_1_10_2","first-page":"433","article-title":"HLA class II studies in 509 narcoleptic patients","volume":"26","author":"Mignot E","year":"1997","journal-title":"Sleep Res"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(92)90571-J"},{"key":"e_1_2_1_12_2","first-page":"181","volume-title":"Sleep and its disorders in children","author":"Guilleminault C","year":"1987"},{"key":"e_1_2_1_13_2","first-page":"434","article-title":"DQB1\u20100602 negative narcolepsy a different trigger for cataplexy","volume":"26","author":"Mignot E","year":"1997","journal-title":"Sleep Res"},{"key":"e_1_2_1_14_2","first-page":"527","article-title":"Modafinil for the treatment of pathological somnolence in patients with narcolepsy","volume":"26","author":"Mitler M","year":"1997","journal-title":"Sleep Res"}],"container-title":["Annals of Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fana.410430125","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/ana.410430125","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T19:23:31Z","timestamp":1698521011000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/ana.410430125"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,1]]},"references-count":13,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,1]]}},"alternative-id":["10.1002\/ana.410430125"],"URL":"https:\/\/doi.org\/10.1002\/ana.410430125","archive":["Portico"],"relation":{},"ISSN":["0364-5134","1531-8249"],"issn-type":[{"value":"0364-5134","type":"print"},{"value":"1531-8249","type":"electronic"}],"subject":[],"published":{"date-parts":[[1998,1]]}}}