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We computed continuous wavelet transforms of the signals and correlated (1) baseline spectral power and motor symptom severity and (2) changes in spectral power and contralateral motor symptoms related to microlesion.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Baseline motor symptom severity correlated with high\u2010frequency broadband power in primary motor cortex during voluntary movements (200\u2013300Hz: Pearson's r\u2009=\u20090.51,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014, 95% confidence interval [CI]: [0.15, 0.75]; and 300\u2013500Hz: r\u2009=\u20090.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.038, 95% CI: [0.06, 0.70]). Motor improvements from lead implant correlated with decreases in high gamma power in primary sensory cortex during voluntary movements (70\u2013200Hz: r\u2009=\u20090.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.035, 95% CI: [\u22120.07, 0.62]).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Interpretation<\/jats:title>\n                    <jats:p>How motor parkinsonism alters electrophysiology in cerebral cortex is unclear. Our findings suggest that both the severity of parkinsonism and its improvement from the microlesion effect are associated most closely with changes in high\u2010frequency oscillatory activity in primary sensorimotor cortex. Better understanding the cortical dynamics of movement disorders could guide novel paradigms for adaptive DBS. ANN NEUROL 2026;99:480\u2013491<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/ana.78077","type":"journal-article","created":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T10:41:09Z","timestamp":1761907269000},"page":"480-491","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Sensorimotor Cortex High Frequency Oscillations Characterize Motor Symptom Severity during\n                    <scp>Deep Brain Stimulation<\/scp>\n                    Surgery for Parkinson's Disease"],"prefix":"10.1002","volume":"99","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0871-0758","authenticated-orcid":false,"given":"Jeevan K.","family":"Jadapalli","sequence":"first","affiliation":[{"name":"Department of Neurology University of Alabama at Birmingham  Birmingham AL 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