{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T12:49:07Z","timestamp":1790254147258,"version":"4.1.0"},"reference-count":27,"publisher":"Wiley","issue":"32","license":[{"start":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T00:00:00Z","timestamp":1153180800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2006,8,11]]},"DOI":"10.1002\/anie.200601808","type":"journal-article","created":{"date-parts":[[2006,7,18]],"date-time":"2006-07-18T09:16:48Z","timestamp":1153214208000},"page":"5364-5368","source":"Crossref","is-referenced-by-count":37,"title":["Synthesis of Highly Substituted <i>N<\/i>\u2010Hydroxyindoles through 1,5\u2010Addition of Carbon Nucleophiles to In Situ Generated Unsaturated Nitrones"],"prefix":"10.1002","volume":"45","author":[{"given":"K. C.","family":"Nicolaou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony A.","family":"Estrada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Hyup","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Graeme C.","family":"Freestone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2006,8,7]]},"reference":[{"key":"e_1_2_2_1_2","doi-asserted-by":"publisher","DOI":"10.1002\/ange.200500724"},{"key":"e_1_2_2_1_3","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200500724"},{"key":"e_1_2_2_2_2","unstructured":"\u00a0"},{"key":"e_1_2_2_3_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.56.226"},{"key":"e_1_2_2_4_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.56.232"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja026249t"},{"key":"e_1_2_2_6_2","unstructured":"nocathiacin antibiotics:J. E.Leet H. A.Ax D. R.Gustavson D. M.Brown L.Turner K.Brown W.Li K. S.Lam WO 2000003722A1 ["},{"key":"e_1_2_2_6_3","first-page":"121531","volume":"132","year":"2000","journal-title":"Chem. Abstr."},{"key":"e_1_2_2_7_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.51.715"},{"key":"e_1_2_2_8_2","unstructured":"For selected reviews onN\u2010hydroxyindoles and their derivatives see:"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2725(02)82027-X"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.3987\/REV-98-SR(H)8"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2725(08)60002-1"},{"key":"e_1_2_2_12_2","unstructured":"\u00a0"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2005.10.165"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo051609r"},{"key":"e_1_2_2_15_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo035351l"},{"key":"e_1_2_2_16_2","doi-asserted-by":"publisher","DOI":"10.1021\/ja0372006"},{"key":"e_1_2_2_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/jo010002h"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(97)00208-1"},{"key":"e_1_2_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cber.19040370416"},{"key":"e_1_2_2_20_2","unstructured":"This type of reaction is sometimes referred to as a 1 4\u2010addition."},{"key":"e_1_2_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)61635-5"},{"key":"e_1_2_2_22_2","unstructured":"CCDC 603155 (19) and 603156 (23) contain the supplementary crystallographic data for this paper. These data can be obtained free of charge from The Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk\/data_request\/cif."},{"key":"e_1_2_2_23_2","unstructured":"\u00a0"},{"key":"e_1_2_2_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1139(01)00477-8"},{"key":"e_1_2_2_25_2","doi-asserted-by":"publisher","DOI":"10.1039\/a903681d"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanie.200601808","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.200601808","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T09:33:18Z","timestamp":1697448798000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.200601808"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,8,7]]},"references-count":27,"journal-issue":{"issue":"32","published-print":{"date-parts":[[2006,8,11]]}},"alternative-id":["10.1002\/anie.200601808"],"URL":"https:\/\/doi.org\/10.1002\/anie.200601808","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,8,7]]}}}