{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:02:25Z","timestamp":1762542145404},"reference-count":34,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2012,11,12]],"date-time":"2012-11-12T00:00:00Z","timestamp":1352678400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Angew Chem Int Ed"],"published-print":{"date-parts":[[2013,1,7]]},"DOI":"10.1002\/anie.201206561","type":"journal-article","created":{"date-parts":[[2012,11,13]],"date-time":"2012-11-13T01:39:27Z","timestamp":1352770767000},"page":"562-567","source":"Crossref","is-referenced-by-count":13,"title":["Discovery of a Novel Aggregation Domain in the Huntingtin Protein: Implications for the Mechanisms of Htt Aggregation and Toxicity"],"prefix":"10.1002","volume":"52","author":[{"given":"Zhe\u2010Ming","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hilal A.","family":"Lashuel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,11,12]]},"reference":[{"key":"e_1_2_2_1_2","unstructured":"\u00a0"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70178-4"},{"key":"e_1_2_2_3_2","first-page":"1202","volume":"60","author":"Brinkman R. R.","year":"1997","journal-title":"Am. J. Hum. Genet."},{"key":"e_1_2_2_4_2","unstructured":"\u00a0"},{"key":"e_1_2_2_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2008.06310.x"},{"key":"e_1_2_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-006-6242-0"},{"key":"e_1_2_2_7_2","unstructured":"\u00a0"},{"key":"e_1_2_2_8_2","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.15.9158"},{"key":"e_1_2_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/00019052-199708000-00003"},{"key":"e_1_2_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13304-1"},{"key":"e_1_2_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/ng0297-197"},{"key":"e_1_2_2_12_2","unstructured":"\u00a0"},{"key":"e_1_2_2_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-8628(19960216)67:1<53::AID-AJMG9>3.0.CO;2-T"},{"key":"e_1_2_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.31.5.377"},{"key":"e_1_2_2_15_2","unstructured":"\u00a0"},{"key":"e_1_2_2_16_2","doi-asserted-by":"publisher","DOI":"10.1006\/jmbi.2001.4850"},{"key":"e_1_2_2_17_2","doi-asserted-by":"publisher","DOI":"10.1021\/bi700806c"},{"key":"e_1_2_2_18_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1570"},{"key":"e_1_2_2_19_2","unstructured":"\u00a0"},{"key":"e_1_2_2_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/5.12.1875"},{"key":"e_1_2_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(00)80764-3"},{"key":"e_1_2_2_22_2","unstructured":"\u00a0"},{"key":"e_1_2_2_23_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl440"},{"key":"e_1_2_2_24_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1409-03.2004"},{"key":"e_1_2_2_25_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.262544899"},{"key":"e_1_2_2_26_2","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.1700"},{"key":"e_1_2_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2005.10.053"},{"key":"e_1_2_2_28_2","unstructured":"\u00a0"},{"key":"e_1_2_2_29_2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503634102"},{"key":"e_1_2_2_30_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/8.3.397"},{"key":"e_1_2_2_31_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1305-11.2012"},{"key":"e_1_2_2_32_2","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-06-02193.2003"},{"key":"e_1_2_2_33_2","doi-asserted-by":"publisher","DOI":"10.1110\/ps.42301"},{"key":"e_1_2_2_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr040"}],"container-title":["Angewandte Chemie International Edition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1002%2Fanie.201206561","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/anie.201206561","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T23:44:23Z","timestamp":1697499863000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/anie.201206561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,12]]},"references-count":34,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,1,7]]}},"alternative-id":["10.1002\/anie.201206561"],"URL":"https:\/\/doi.org\/10.1002\/anie.201206561","archive":["Portico"],"relation":{},"ISSN":["1433-7851","1521-3773"],"issn-type":[{"value":"1433-7851","type":"print"},{"value":"1521-3773","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,12]]}}}