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The key steps included the regioselective installation of two amino sugars (<jats:sc>L<\/jats:sc>\u2010vancosamine and <jats:sc>D<\/jats:sc>\u2010angolosamine) on the tricycle and the efficient construction of the tetracyclic skeleton by an aldol reaction followed by formation of the pyranone. The unknown configuration at C14 was assigned as <jats:italic>R<\/jats:italic>.<\/jats:p>","DOI":"10.1002\/anie.201308017","type":"journal-article","created":{"date-parts":[[2013,12,16]],"date-time":"2013-12-16T20:37:00Z","timestamp":1387226220000},"page":"1262-1265","source":"Crossref","is-referenced-by-count":48,"title":["Synthesis of the Pluramycins 2: Total Synthesis and Structure Assignment of Saptomycin\u2005B"],"prefix":"10.1002","volume":"53","author":[{"given":"Kei","family":"Kitamura","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshihiko","family":"Maezawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshio","family":"Ando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takenori","family":"Kusumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takashi","family":"Matsumoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2013,12,16]]},"reference":[{"key":"e_1_2_2_1_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.46.1530"},{"key":"e_1_2_2_2_2","doi-asserted-by":"publisher","DOI":"10.7164\/antibiotics.46.1536"},{"key":"e_1_2_2_3_2","unstructured":"\u00a0"},{"key":"e_1_2_2_4_2","first-page":"75","volume":"9","author":"Maeda K.","year":"1956","journal-title":"J. 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